Hoong-Wei Gan

Monogenic diabetes mellitus in cystic fibrosis Hoong-Wei Gan1,2, Jayesh Mahendra Bhatt3, Louise Denvir1, Tabitha Randell1, Pooja Sachdev1 1 Department of Paediatric Endocrinology, Nottingham Children’s Hospital, Nottingham University Hospitals NHS Trust, Nottingham, UK 2 Genetics and Genomic Medicine Programme, University College London Great Ormond Street Institute of Child Health, London, UK 3 Department of Paediatric Respiratory Medicine, Nottingham Children’s Hospital, Nottingham...

Five-year childhood cancer survival rates have increased to 80–90% for some tumours due to intensified treatments and better supportive care imposed on an incidence stable over four decades.1 ,2 Between 2005 and 2012, the number of UK survivors has risen from 26 000 to 33 000, or from 1:1000 to 1:715 UK adults.3 ,4 However, 40% experience chronic severe or life-threatening consequences (‘late effects’) of their tumour and/or its treatment.5 The recent National Cancer Survivorship Initiative...