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Housaiyin Li

As seen in: The BMJ, Cell Press
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Articles

Distinct CD8+ T cell dynamics associate with response to neoadjuvant cancer immunotherapies

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By Housaiyin Li, Dan P. Zandberg, Aditi Kulkarni, Simion I. Chiosea, Patricia Santos, Brian R. Isett, Marion Joy, Gabriel Sica, Kevin J. Contrera, Curtis Tatsuoka, Matthias Brand, Umamaheswar Duvvuri, Seungwon Kim, Mark W. Kubik, Shaum Sridharan, Jie Chen, Tullia C. Bruno, Dario A.A. Vignali, Anthony R. Cillo, Riyue Bao, Jing Wang, Lazar Vujanovic, Robert Ferris Verified
| Cell Press Verified
Keywords Head and neck cancer tumor immunology clinical trial single-cell genomics T cell dynamics multispectral imaging combination immunotherapy PD-1 LAG-3 CTLA-4 Introduction While monoclonal antibodies (mAb) targeting the PD-1/PD-L1 pathway have transformed cancer treatment, durable responses are observed only in a minority of cancer patients.1,2,3,4 The limited clinical efficacy of cancer immunotherapy highlights the need to identify reliable markers that can predict responses to immune...
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Differential impact of TIM-3 ligands on NK cell function

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By Juncheng Wang, Aditi Kulkarni, Jennifer Anderson, Housaiyin Li
| The BMJ Verified
Methods K562 cell line was obtained from American Type Culture Collection (Manassas, Virginia, USA).
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