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Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease
Metabolic syndrome (MetS) is a term used to characterize individuals having at least three of the following diseases: obesity, dyslipidemia, hyperglycemia, insulin resistance, hypertension, and nonalcoholic fatty liver disease (NAFLD). It is widespread, and the number of individuals with MetS is increasing. However, the events leading to the manifestation of MetS are not well-understood. Here, we show that loss of murine ARV1 (mARV1) results in resistance to acquiring diseases associated with MetS.
Mice lacking ARV1 have reduced signs of metabolic syndrome and non-alcoholic fatty liver disease
MetS syndrome (MetS) is a term used to characterize individuals having at least three of the following diseases: obesity, dyslipidemia, hyperglycemia, insulin resistance, hypertension, and non-alcoholic fatty liver disease (NAFLD). It is widespread and the number of individuals with MetS is increasing. However, the events leading to the manifestation of MetS are not well understood. Here, we show that loss of mARV1 in mice results in resistance to acquiring diseases associated with MetS.
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