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Abstract Circular RNAs (circRNAs) are emerging as important regulators in mammalian cells and promising substrates for RNA therapeutics, yet the trans-acting factors governing their metabolism remain poorly defined. Here we systematically evaluate 730 RNA-binding proteins (RBPs) using a tethered reporter assay and identify 281 RBPs that significantly modulate circRNA activity.
As a journalist, you can create a free Muck Rack account to customize your profile, list your contact preferences, and upload a portfolio of your best work.
