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Hua-Hui Ho on Muck Rack

Hua-Hui Ho

As seen in: Journal of Biomedical Science
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Cysteine-rich protein 2 deficiency attenuates angiotensin II-induced abdominal aortic aneurysm formation in mice - Journal of Biomedical Science

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By Wai-Sam Ao-Ieong, Jane Wang, Alexander N. Orekhov, Shaw-Fang Yet, Chung-Huang Chen, Hua-Hui Ho, Wei-Cheng Jiang, Igor A. Sobenin, Matthew D. Layne
| Journal of Biomedical Science Verified
Journal of Biomedical Science volume 29, Article number: 25 (2022) Cite this article Abstract Background Abdominal aortic aneurysm (AAA) is a relatively common and often fatal condition. A major histopathological hallmark of AAA is the severe degeneration of aortic media with loss of vascular smooth muscle cells (VSMCs), which are the main source of extracellular matrix (ECM) proteins. VSMCs and ECM homeostasis are essential in maintaining structural integrity of the aorta.
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