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Huangtian Yang on Muck Rack

Huangtian Yang

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PRIME-HFrEF Trial: a randomized, double-blind, multi-dose umbilical cord-derived mesenchymal stem cell regimen for heart failure

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By Wei Han, Yuheng Jiao, Xin Gong, Hao Hu, Yuanfeng Xin, Jun Zhao, Qi Zhang, Jingwei Pan, Haiyan Wang, Qing Lu, Shuguang Chu, Dihui Cai, Liang Zheng, Wenwen Jia, Zhiying He, Yi Sun, Zhongmin Liu, Sibin Guan, Huangtian Yang
| Nature Verified
Abstract The safety of multi-dose mesenchymal stem cell (MSC) regimens has seldom been systematically investigated. The PRIME-HFrEF (Prospective Randomized Controlled Study of Multiple Intravenous Infusions of Umbilical Cord–derived MSCs in Patients with Heart Failure and Reduced Ejection Fraction) trial was a single-center, randomized, placebo-controlled, investigator-initiated study (ClinicalTrials.gov identifier: NCT04992832) that enrolled 40 patients.
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