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Xin Gong

As seen in: AIChE Journal, British Ecological Society (Wiley), Nature, Wiley Online Library, MDPI, SAGE Publishing, Flipboard, Science Magazine, BioRxiv, Cell Press and
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Articles

Atmospheric black carbon in the climate system

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By Örjan Gustafsson, Krishnakant Budhavant, Sean Clarke, Gabrielle B Dreyfus, Xin Gong, Zbigniew Klimont, Klaus Klingmüller, Sang-Woo Kim, Jos Lelieveld, Gunnar Myhre, Jianfei Peng, V. Ramanathan, M. Manoj, S. K. Satheesh, Chandra Venkataraman, Qiang Zhang, Navinya Chimurkar, H.R.C.R. Nair, Archita Rana
| Flipboard
Black carbon (BC) aerosols are short-lived climate pollutants with important, but uncertain, climate impacts. In this Review, we synthesize …
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Structural and functional dissection of a higher-order oligomerization interface in yeast ceramide synthase

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By Qi Fang, Chang Yeol Yang, Nan Yao, Tian Yu Xie, Xin Gong
| Nature Verified
Abstract Ceramide synthases (CerSs) are crucial enzymes in sphingolipid metabolism and have shown therapeutic potential for treating various metabolic disorders. However, their regulatory mechanisms remain poorly understood. In this study, we report the cryo-electron microscopy structure of a yeast CerS (yCerS), composed of a catalytic Lac1 subunit and a regulatory Lip1 subunit, organized into a higher-order 4:4 assembly.
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PRIME-HFrEF Trial: a randomized, double-blind, multi-dose umbilical cord-derived mesenchymal stem cell regimen for heart failure

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By Wei Han, Yuheng Jiao, Xin Gong, Hao Hu, Yuanfeng Xin, Jun Zhao, Qi Zhang, Jingwei Pan, Haiyan Wang, Qing Lu, Shuguang Chu, Dihui Cai, Liang Zheng, Wenwen Jia, Zhiying He, Yi Sun, Zhongmin Liu, Sibin Guan, Huangtian Yang
| Nature Verified
Abstract The safety of multi-dose mesenchymal stem cell (MSC) regimens has seldom been systematically investigated. The PRIME-HFrEF (Prospective Randomized Controlled Study of Multiple Intravenous Infusions of Umbilical Cord–derived MSCs in Patients with Heart Failure and Reduced Ejection Fraction) trial was a single-center, randomized, placebo-controlled, investigator-initiated study (ClinicalTrials.gov identifier: NCT04992832) that enrolled 40 patients.
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