Huanyang He on Muck Rack

Huanyang He

As seen in: Frontiers
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Articles

Significant association of RANKL polymorphisms with bone metastasis among patients with breast cancer

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By Haoyu Lian, Siyuan Zhou, Huanyang He, Qian Liu, Jinmin Zhao
| Frontiers
Abstract Objective: The purpose of this study was to reveal the genetic correlation of RANKL polymorphisms with bone metastasis in breast cancer patients. Methods: In this study, 139 bone metastasis patients and 152 no metastasis were included as the case and control groups. Real-time polymerase chain reaction (PCR) and allelic discrimination method were respectively applied for the genotyping of rs7325635 and rs2277438.
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Transcriptomic analysis reveals TME-mediated macrophage IFIT1 upregulation and CX3CR1 suppression drive osteosarcoma progression

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By Keyi Wang, Jiamin Liang, Yuangang Su, Jinmin Zhao, Qian Liu, Huanyang He
| Frontiers
1 Introduction Osteosarcoma (OS), a highly prevalent primary bone malignancy, predominantly occurs in adolescents and young adults (1). Despite multimodal therapies, the prognosis for patients with OS remains poor due to tumor heterogeneity and complex molecular mechanisms (2, 3).
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