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Siyuan Zhou on Muck Rack

Siyuan Zhou

As seen in: Nature, Wiley Online Library, Frontiers, MDPI, Taylor & Francis Online, Molecular Cancer, Royal Society of Chemistry, BioRxiv, Dove Medical Press, Optica and
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Articles

Mitochondrial Dysfunction in Ulcerative Colitis: Pathogenic Mechanisms and Novel Therapeutics

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By Bioengineering Chongqing, Siyuan Zhou, Hongyan Ran
| Wiley Online Library Verified
1 Introduction Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized by persistent mucosal inflammation, compromised epithelial barrier integrity, and dysregulated immune homeostasis [1, 2]. A growing body of evidence identifies mitochondrial dysfunction as a central driver of UC pathogenesis via multiple interconnected mechanisms.
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Inhibiting glucocorticoid receptors enhances adult spinal cord neural stem cell activity and improves outcomes in spinal cord injury

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By Xuefeng Zhang, Siyuan Zhou, Shengyu Tang, Xiaotong Hou, Yonghui Cai, Changlong Hu
| Nature Verified
Abstract The spinal cord injury (SCI) microenvironment undergoes significant biochemical changes that influence the behavior of endogenous neural stem/progenitor cells (NSPCs), including elevated glucocorticoid levels. Here, we investigate the effects of glucocorticoids on NSPCs in the adult mouse spinal cord. Adult spinal cord NSPCs express glucocorticoid receptors but not mineralocorticoid receptors.
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Neuroergonomic evaluation of risk-warning eHMI penetration rates in vehicle platoons: effects on pedestrians’ mental workload, situation awareness, and gap acceptance

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By Fang Yang, Xu Sun, Jing Ma, Siyuan Zhou, Bingjian Liu, Puhong Li, Wei Lyu, Shijiang Wen
| Nature Verified
Abstract The deployment of Level 4–5 autonomous vehicles (AVs) in real traffic environments presents significant challenges for pedestrian interaction, primarily due to the absence of human driver cues. To address this limitation, risk-warning external human–machine interfaces (eHMIs), which communicate dynamic crossing risks based on the AV’s time-to-arrival (TTA), have received growing attention.
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