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Huee Ru Chong

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Articles

Essential role of VGLUT2-negative claustro-prefrontal projections in working memory

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By Jia Tan, Huee Ru Chong, Xuan OuYang, Priya Ramesh, Martin Graf, George J. Augustine, Tsukasa Kamigaki
| Cell Press Verified
Results To examine the brain-wide connectivity of the VGLUT2-negative projection neurons in the claustrum (CLA), VGLUT2-Cre mice were injected with two adeno-associated virus (AAV) constructs: (1) Flp-encoding retrograde AAV (AAVrg) injected into the medial prefrontal cortex (mPFC), enabling Flp recombinase (Flippase) to be retrogradely transported to mPFC-projecting neurons (AAVrg-Flp; Figure 1A), and (2) CreOFF/FlpON-oScarlet-encoding AAV injected into the CLA.
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