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Articles by Hung Le
Outcomes of early-onset vs average-onset colorectal cancer patients on phase I matched and non-matched therapies
Abstract Early-onset colorectal cancer (EOCRC) is an increasingly prevalent disease with no age-specific therapies despite evidence suggesting biologic differences between EOCRC and average-onset CRC (AOCRC).
Obstacles to business growth and how to overcome them
Business growth can be exciting, but it rarely comes without pressure. As your company expands, new opportunities can open up for your customers, your workforce, and the business as a whole. But growth can also expose weaknesses in your processes, finances, systems, and management structure. The work ethic that helped you get started may not be enough to support the next stage. That’s why it’s important to anticipate the business challenges that can arise as your project grows.
Novel Immunotherapy Agents in Early-Phase Trials for Head and Neck Cancer
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Supplement 1. eMethods 1. Translational Correlates eMethods 2. Model Assumption Testing eTable 1. Viral Status and Molecular Findings eTable 2. Investigational Immuno-Oncology Treatment Profile eTable 3. Best Overall Responses in the Study Cohort eTable 4. Factors Associated With Clinical Benefit Rate eTable 5. Factors Associated With PFS eTable 6. Factors Associated With OS eFigure 1. Study Cohort Flow Diagram eFigure 2. PD-L1 Expression by Anatomic Site eFigure 3.
By Harold Nathan Tan, Bettzy Stephen, Oriol Mirallas, Mohamed H. Derbala, Israa Fouad Salih, Hung Le, Hùng Lê, Heather Y. Lin, Joann G. Lim, Ecaterina E. Dumbrava, Timothy A. Yap, Jordi Rodon, Sarina Piha-Paul, Siqing Fu, Stéphane Champiat, Neal S. Akhave, Renata Ferrarotto, David Hong, Funda Meric-Bernstam, Faye M. Johnson, Aung Naing, Lilibeth Castillo
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JAMA Network
Verified
DP21676 Competition or Collusion? Entry Decisions in the Swedish Pharmaceutical Market
English Français Deutsch Italiano 中文 More Español Ελληνικά 日本語 Português Türkçe Price regulation may have unintended consequences, such as facilitating collusion or softening actual price competition by causing a reduction in the number of active firms. Observing different firms hav- ing a monopoly position in parts of a market may be the result of either intense post-entry competition and non-cooperative entry decisions, or collusive entry.
Genomic co-alterations and immune-related adverse events shape outcomes of thymic malignancies treated with immune checkpoint inhibitors
Abstract Thymic carcinoma, thymoma, and thymic neuroendocrine tumors are rare malignancies with limited treatment options in advanced stages. Immune checkpoint inhibitors (ICIs) have shown preliminary activity in thymic tumors, although their clinical benefit and toxicity profile remain incompletely defined. We retrospectively analyzed patients with thymic tumors treated with ICIs at MD Anderson Cancer Center from 2010 to 2024.
300 trẻ em khó khăn được khám sức khỏe, tư vấn dinh dưỡng miễn phí
Chương trình được triển khai với mong muốn góp phần nâng cao nhận thức chăm sóc sức khỏe và dinh dưỡng cho trẻ em đồng bào dân tộc thiểu số – nhóm đối tượng còn gặp nhiều hạn chế trong việc tiếp cận các dịch vụ y tế và kiến thức dinh dưỡng phù hợp.
We need to think smaller not bigger to future-proof AI
Datasets used to train AI algorithms may underrepresent older people. Credit: Pixabay/CC0 Public Domain In the last few years, many of us have started to see the benefits of using genAI in day-to-day tasks. But we've also been asked to reckon with the enormous environmental cost. Reporting has highlighted that these popular AI technologies have a significant environmental impact through high energy consumption, carbon emissions, and water use.
Minimized sample consumption for time-resolved serial crystallography applied to the redox cycle of human NQO1 - Communications Chemistry
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Abstract Sample consumption for serial femtosecond crystallography with X-ray free electron lasers remains a major limitation preventing broader use in macromolecular crystallography. This drawback is exacerbated in time-resolved (TR) experiments, where the amount of sample required per reaction time point is multiplied by the number of time points investigated.
By Diandra Doppler, Abhik Manna, Hung Le, Hùng Lê, Mukul Sonker, Gihan Ketawala, Romain Letrun, Katerina Dorner, Raphael de Wijn, Johan Bielecki, Huijong Han, Chan Kim, Adam Round, Abhisakh Sarma, Tokushi Sato, Christina Schmidt, Mohammad Ghazi Vakili, Richard Bean, Joachim Schulz, Raimund Fromme, Milagros Medina, Thomas Grant, Petra Fromme, Richard A. Kirian, Sabine Botha, José Martín-García, Sayantee Sen
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Nature
Verified
Spreading love and support to help disadvantaged border students head back to school
The Vietnam Fatherland Front Committee of Hung Phuoc Commune, in coordination with SNP Company Limited (VSIP II Industrial Park, Ho Chi Minh City), visited, presented gifts, and awarded scholarships to ethnic minority students in difficult circumstances in Area 134, Muoi Mau Hamlet, Hung Phuoc Commune (Dong Nai Province). The delegation brought practical gifts to encourage students and give them greater confidence as they enter the new school year.
For the peaceful life of the people
During the 80-year journey of building, fighting and growing up, the image of the Vietnamese People's Public Security soldiers has become a noble symbol of bravery and wholehearted service to the people. In Dong Nai - a land rich in economic potential and a key area in terms of security and order, the Provincial Public Security force has been affirming its core role in maintaining peace for the people, ensuring a stable environment for investment and development.
Campuchia tổng lực truy quét lừa đảo trực tuyến
Theo thông báo từ Bộ Nội vụ Campuchia, chỉ trong vòng vài tuần qua, hàng ngàn đối tượng có liên quan đến các đường dây lừa đảo công nghệ cao đã bị bắt giữ. Từ đầu tháng 7, cảnh sát và các lực lượng chức năng Campuchia đã đồng loạt ra quân tại nhiều địa phương, đặc biệt tại khu vực giáp biên giới với các nước, khu kinh tế đặc biệt và những nơi nghi ngờ có hoạt động của các trung tâm lừa đảo trực tuyến.
Phải tăng nặng trừng trị kẻ cầm gậy bóng chày đánh bố trước mặt con trẻ
Tên côn đồ tấn công người đàn ông đang chở con nhỏ. (Nguồn: Mạng xã hội) Đoạn video đang lan truyền trên mạng xã hội ghi lại cảnh tượng một gã đàn ông lực lưỡng cầm gậy bóng chày đánh tới tấp vào người đi xe máy chở theo con nhỏ. Anh ta làm vậy chỉ để xả cơn tức giận vì ô tô của mình suýt va vào xe máy kia khi qua ngã tư. Hành vi côn đồ, hung hãn ấy làm dấy lên sự phẫn nộ và căm phẫn trong cộng đồng.
[2503.22669] Light Tree Covers, Routing, and Path-Reporting Oracles via Spanning Tree Covers in Doubling Graphs
[Submitted on 28 Mar 2025] Title:Light Tree Covers, Routing, and Path-Reporting Oracles via Spanning Tree Covers in Doubling Graphs View a PDF of the paper titled Light Tree Covers, Routing, and Path-Reporting Oracles via Spanning Tree Covers in Doubling Graphs, by Hsien-Chih Chang and 4 other authors View PDF Abstract:A $(1+\varepsilon)$-stretch tree cover of an edge-weighted $n$-vertex graph $G$ is a collection of trees, where every pair of vertices has a $(1+\varepsilon)$-stretch path in...
[2411.00216] Embedding Planar Graphs into Graphs of Treewidth $O(\log^{3} n)$
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
[2408.14638] New weighted additive spanners
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
[2407.12230] Optimal Padded Decomposition For Bounded Treewidth Graphs
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
The Integrating Impacts of Extreme Weather Events and Shrimp Farming Practices on Coastal Water Resource Quality in Ninh Thuan Province, Vietnam
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Sales of locally assembled cars lower than imported vehicles
HCMC – The first five months of this year saw more completely built-up cars (CBU) sold than locally assembled units, according to the Vietnam Automobile Manufacturers Association (VAMA). A VAMA report, released on June 11, showed that total market sales in May reached 25,794 units, including 18,235 passenger cars, 7,292 commercial vehicles, and 267 special-use automobiles, up by 6%, 7% and 4% against the previous month, respectively.
On the road to recovery
Vietnam’s real estate market is now on the brink of a major transformation after a long challenging period induced by the supply-demand imbalance, legal issues, and wide disparities between housing prices and incomes. Despite the persistent headwinds, there are high hopes for a rebound.
Chatting Up the Next Big Thing: Generating Novel Ideas for Systematic Reviews in Breast Reconstruction Research Using Chat-GPT
Specialty Please choose I'm not a medical professional. Allergy and Immunology Anatomy Anesthesiology Biostatistics Cardiac/Thoracic/Vascular Surgery Cardiology Critical Care Dentistry Dermatology Diabetes and Endocrinology Emergency Medicine Epidemiology and Public Health Family Medicine Forensic Medicine Gastroenterology General Practice Genetics Geriatrics Health Policy Hematology HIV/AIDS Hospital-based Medicine I'm not a medical professional.
Council Post: Strengthening Cybersecurity Resilience For Organizations In The Asia-Pacific Region: A Comprehensive Approach
Dr. Cuong currently serves as Chief Digital Officer of FPT Digital, a consulting firm of FPT Corporation. Data breaches have become a raising concern in today's digital landscape, impacting organizations of all sizes and across various industries. When it comes to ransomware and security breaches, no organization is exempt from the threat.
Man stuck in 30-cm crevice while retrieving phone in central Vietnam
By Hung Le  June 2, 2024 | 12:48 am PT Police in Ha Tinh Province have rescued a man after he got stuck down a gap 30 cm wide and 2 meters deep between two walls. Around 8:50 p.m. on Saturday Hoang Phuc Sen, 53, residing in Ha Tinh City in the namesake province, dropped his phone into the gap between his and the neighboring house. Sen removed a window frame, climbed down into the gap to pick up the phone, and got trapped between the concrete foundations.
Promising growth of industrial real estate
The industrial real estate sector in Vietnam is exhibiting signs of robust growth, driven by an influx of foreign manufacturers. These businesses are choosing Vietnam as their investment destination, attracted by opportunities for supply chain diversification and market expansion.
Tôi vô sinh nhưng vợ lại có thai
Cách đây vài ngày, trong lúc đi mua sắm, tôi tình cờ gặp lại Cường, cậu bạn chung của tôi và vợ cũ - Hằng. Qua một lúc trò chuyện, tôi không khỏi choáng váng khi biết được vợ cũ đi rêu rao, bêu xấu tôi khắp nơi. Trong câu chuyện của cô ấy, chúng tôi ly hôn vì tôi bạo hành vợ khi cô ấy đang mang thai. Trong lúc giận dữ, cô ấy quyết định ly dị, rời đi và hiện tại vẫn độc thân, một mình nuôi con vô cùng vất vả.
Tôi vô sinh nhưng vợ lại có thai
Cách đây vài ngày, trong lúc đi mua sắm, tôi tình cờ gặp lại Cường, cậu bạn chung của tôi và vợ cũ - Hằng. Qua một lúc trò chuyện, tôi không khỏi choáng váng khi biết được vợ cũ đi rêu rao, bêu xấu tôi khắp nơi. Trong câu chuyện của cô ấy, chúng tôi ly hôn vì tôi bạo hành vợ khi cô ấy đang mang thai. Trong lúc giận dữ, cô ấy quyết định ly dị, rời đi và hiện tại vẫn độc thân, một mình nuôi con vô cùng vất vả.
Tôi vô sinh nhưng vợ lại có thai
Theo dõi VGT trên Tôi bị vợ đầu bỏ vì không có khả năng làm cha, vậy mà người vợ thứ hai lại có thai sau hơn 2 năm chung sống; tôi không thể nói ra sự thật này vì sĩ diện. Cách đây vài ngày, trong lúc đi mua sắm, tôi tình cờ gặp lại Cường, cậu bạn chung của tôi và vợ cũ – Hằng. Qua một lúc trò chuyện, tôi không khỏi choáng váng khi biết được vợ cũ đi rêu rao, bêu xấu tôi khắp nơi. Trong câu chuyện của cô ấy, chúng tôi ly hôn vì tôi b.ạo h.ành vợ khi cô ấy đang mang thai.
Tôi vô sinh nhưng vợ lại có thai
Cách đây vài ngày, trong lúc đi mua sắm, tôi tình cờ gặp lại Cường, cậu bạn chung của tôi và vợ cũ - Hằng. Qua một lúc trò chuyện, tôi không khỏi choáng váng khi biết được vợ cũ đi rêu rao, bêu xấu tôi khắp nơi. Trong câu chuyện của cô ấy, chúng tôi ly hôn vì tôi bạo hành vợ khi cô ấy đang mang thai. Trong lúc giận dữ, cô ấy quyết định ly dị, rời đi và hiện tại vẫn độc thân, một mình nuôi con vô cùng vất vả.
Offshore wind power faces headwinds
Despite its vast potential, Vietnam’s offshore wind power sector is grappling with the lack of a legal framework. Whether the targets in National Power Development Plan VIII will be achievable is uncertain. Investment opportunities Kudryashov Sergei Ivanovich, general director of Zarubezhneft, a prominent Russian oil and gas company with a longstanding partnership with Vietnam Oil and Gas Group (PetroVietnam), visited Vietnam in early April.
Antibacterial Zirconia Surfaces from Organocatalyzed Atom-Transfer Radical Polymerization
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
[2403.17754] Optimal Euclidean Tree Covers
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
Impact of internal remittance on households' use of bank services: evidence from Vietnam
Impact of internal remittance on households' use of bank services: evidence from Vietnam Autores: Thu Thi Hoai Nguyen, Hung Manh Le, Le Quoc Hoy, Hang Thu Pham Localización: Journal of Economics, Finance and Administrative Science, ISSN-e 2218-0648, ISSN 2077-1886, Vol. 27, Nº. 53, 2022, págs. 139-153 Idioma: inglés Enlaces Texto completo Resumen This study estimates impact of remittances from internal migration on households' use of bank services in Vietnam.
[2401.12881] Computing Diameter+2 in Truly Subquadratic Time for Unit-Disk Graphs
arXivLabs is a framework that allows collaborators to develop and share new arXiv features directly on our website. Both individuals and organizations that work with arXivLabs have embraced and accepted our values of openness, community, excellence, and user data privacy. arXiv is committed to these values and only works with partners that adhere to them. Have an idea for a project that will add value for arXiv's community? Learn more about arXivLabs.
Retailers grappling with price competition
As consumers grapple with economic hardships, retailers find themselves embroiled in an increasingly fierce price war. However, pricing pressures are just one aspect of a larger issue which vendors at traditional wet markets are dealing with.
Expecting new FDI influx
Experts expect a continued flow of FDI into the country, particularly in the semiconductor industry, and high-tech and value-added products. A roller-coaster ride After serving as a key economic driver for several years, foreign direct investments (FDI) faced a challenging period in 2022, experiencing an 11% year-on-year decline. This cautious investor sentiment continued into the first half of 2023, impacting global investment trends and Vietnam’s economy.
Forest Tales? Unravelling Divergent Land Use and Land Cover Change (LULCC) Maps and State Narratives in Vietnam’s Northern Uplands
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Antibiofilm and Antivirulence Properties of 6-Polyaminosteroid Derivatives against Antibiotic-Resistant Bacteria
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Price wars on e-commerce platforms
E-commerce platforms in Vietnam are not only experiencing fierce competition when it comes to product prices but also engaging in a significant race to lower shipping fees among logistics providers. Aggressive pricing Manufacturers and business owners are increasingly relying on online channels as a powerful tool for brand development, viewing it as a fast and efficient means to boost sales. However, price competition on these platforms is becoming increasingly intense.
Honda Vietnam gears for greener business
Automobiles and motorcycles, needless to say, are a major source of pollution in Vietnam, and in this industry, especially when it comes to motorcycle manufacturing, Honda Vietnam stands out, with a market share of over 80% as of early this year. The company, however, has set up its own pathway to sustainable development, primarily with environmental protection.
Going green for global market expansion
Major international retailers are eyeing Vietnam as a crucial supplier and are establishing their presence by setting up offices in the country. This increased interest from global retailers presents both opportunities and challenges for Vietnamese suppliers, as product criteria and quality standards are becoming more stringent.
A looming influx of fresh capital
U.S. President Joe Biden’s recent state visit to Vietnam has sparked hopes for a significant upswing in investment activity, particularly in the semiconductor industry. Biden’s Vietnam visit marked a milestone as the two nations elevated their bilateral relations to a comprehensive strategic partnership. The upgrade of bilateral ties is highly expected to further advance the economic development of both countries, especially in science, technology and innovation.
Sustainability drives foreign investment
To maintain its competitiveness in the region and continue attracting foreign direct investment (FDI), Vietnam must adapt to evolving investment preferences and take proactive measures. Emergence of new investors During an industrial real estate forum held in HCMC last week, Choi Kyu Chul, vice chairman of the Korean Chamber of Commerce in Vietnam (KoCham), highlighted South Korea’s seamless integration into the new wave of foreign investment in Vietnam following the Covid-19 pandemic.
Stressful economic challenges
Stubborn economic difficulties have led large numbers of small and medium-sized enterprises (SMEs) to exit the market. Meanwhile, those staying afloat are also struggling on the verge of closure. The lack of policy support and the burden of high interest rates are increasing the possibility of more SMEs going bust. Struggles across sectors Tran Hoai Huu, director of Gia Nhien Company, said economic woes have led to a sharp decline in new orders for their handcrafted wooden sailing products.
Shortcut Partitions in Minor-Free Graphs: Steiner Point Removal, Distance Oracles, Tree Covers, and More
arXiv:2308.00555 (cs) Download a PDF of the paper titled Shortcut Partitions in Minor-Free Graphs: Steiner Point Removal, Distance Oracles, Tree Covers, and More, by Hsien-Chih Chang and 5 other authors Download PDF Submission history From: Shay Solomon [ view email] [v1] Mon, 31 Jul 2023 17:51:00 UTC (807 KB) Bibliographic Tools Bibliographic Explorer Toggle Bibliographic Explorer () Litmaps Toggle Litmaps (What is Litmaps?) scite.ai Toggle scite Smart Citations (What are Smart Citations?)...
HCMC hosts five int'l expos
CMC – Five industrial manufacturing exhibitions were inaugurated at the Saigon Exhibition and Convention Center in District 7, HCMC, on July 19. Two of the five large-scale expos, Vietnam ETE and Enertec Expo 2023, commenced on the morning of July 19 and run until July 21.
Bright spots in challenging market
Amidst the overall gloomy economic conditions faced by manufacturers in both local and international markets, a few businesses are showing positive signs of growth, managing to navigate through challenges to expand their operations. Rare bright spots While the prevailing economic picture is mostly discouraging, there are a few rare bright spots, particularly in the real estate, construction materials, and logistics sectors.
F&B expo opens in HCMC
HCMC – The second HCMC International Exhibition of Food and Beverages (HCMC FOODEX 2023) began to open at the Saigon Exhibition and Convention Center in District 7, HCMC today, June 28. The expo features nearly 250 booths of over 200 domestic and international enterprises in the food industry. Key participants include Vinamilk, Binh Tay Food, Vissan, Cholimex Food, and Satra Group.
Bright spots amid the gloom
Despite weak global consumer demand, many foreign buyers are still looking to Vietnam for sourcing goods and business cooperation. This is crucial for manufacturers and exporters in Vietnam to seize this opportunity to retain existing buyers and attract new customers. Promising opportunities ahead It has been proven that enhancing trade promotion activities is one of the practical solutions to look for new orders, especially in tough economic times.
Using Targeted Nano-Antibiotics to Improve Antibiotic Efficacy against Staphylococcus aureus Infections
This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Hung Le , Emmanuelle Dé , Didier Le Cerf * and Carole Karakasyan Sciences & Technic Faculty, Univ Rouen Normandie, INSA Rouen Normandie, CNRS, PBS UMR 6270, 76000 Rouen, France * Author to whom correspondence should be addressed.
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