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Hwee Ying Lim on Muck Rack

Hwee Ying Lim

As seen in: Nature, Flipboard, Science Magazine, Cell Press
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Articles

Targeting excessive cholesterol deposition alleviates secondary lymphoedema - Nature

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By Hwee Ying Lim, Yuning Zhang, Chung Hwee Thiam, Michaela Taylor, Xuan Han Koh, Sheau Yng Lim, Jasmine Goh, Blake J. Cochran, Wai Tham, Owen Ang, Yanjun Chen, Federico Torta, Markus Wenk, Kerry-Anne Rye, Veronique Angeli, Wei Siong Ong, Si Hui Ng, Tze Chin Lim, Sebastian Frederik Mause
| Nature Verified
Abstract Lymphoedema is a chronic debilitating disease caused by impaired lymphatic drainage and is characterized by tissue swelling, fat expansion, inflammation and fibrosis1,2. However, the exact mechanisms that drive lymphoedema are poorly understood.
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Septal LYVE1+ macrophages control adipocyte stem cell adipogenic potential

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By Xiaotong Yu, Yanan Hu, Hwee Ying Lim, Ziyi Li
| Science Magazine Verified
Editor’s summary In addition to their role in host defense, macrophages contribute to the development and remodeling of tissues. Yu et al. characterized macrophages found in the adipose tissue of mice on the basis of their gene expression, localization within the tissue, and developmental origin. A subset of macrophages localized in the same tissue microenvironment as adipocyte stem cells and promoted their differentiation into white adipocytes.
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Efficient aortic lymphatic drainage is necessary for atherosclerosis regression induced by ezetimibe

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By M. Ahmed, C. Byrne, Hwee Ying Lim, Chung Hwee Thiam
| Science Magazine Verified
Abstract A functional lymphatic vasculature is essential for tissue fluid homeostasis, immunity, and lipid clearance. Although atherosclerosis has been linked to adventitial lymphangiogenesis, the functionality of aortic lymphatic vessels draining the diseased aorta has never been assessed and the role of lymphatic drainage in atherogenesis is not well understood.
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