Hyo-Eun C. Bhang on Muck Rack

Hyo-Eun C. Bhang

As seen in: Cell Reports
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Structural basis of DNA-dependent coactivator recruitment by the tuft cell master regulator POU2F3

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By Aktan Alpsoy, Jonathan J. Ipsaro, Damianos S. Skopelitis, Sujay Pal, Frank Chung Verified, Shannon L. Carpenter, John J Desmarais, Xiaoli Wu, Kenneth Chang Verified, Matthew T. DiMare, Erin Harten, Staci Bergman, Justin Kinney, Jeffrey A. Engelman, Hyo-Eun C. Bhang, Leemor Joshua-Tor, Christopher R. Vakoc
| Cell Reports Verified
Keywords POU2F3 tuft cell small cell lung cancer OCA-T1 OCA-T2 POU2AF2 POU2AF3 deep mutational scanning X-ray crystallography Research topic(s) CP: molecular biology CP: cancer Introduction Most human cancers can be classified based on their resemblance to specific normal cell types, which is often reflected in the histological appearance or transcriptome of a tumor.1 While cancer cell identity can be dynamic and evolve in response to selection pressures, it is often sufficiently stable to...
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