Hyperbaric Medicine
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Hyperbaric oxygen preconditioning alleviates spinal cord injury by inhibiting pro-inflammatory astrocyte polarization in a rat model of decompression sickness
Abstract Decompression sickness (DCS) spinal cord injury (SCI) is a pivotal concern in diving activities, and prevention is the key. Our previous study found that hyperbaric oxygen (HBO) preconditioning reduced neurological deficit in DCS SCI rats, but the underlying mechanisms remain unclear. This study examined pro-inflammatory astrocyte polarization in DCS SCI rats and determined whether HBO exerts its protective effect by inhibiting this polarization.
Effects of hyperbaric air exposure with oxygen breathing during decompression on the exhaled volatile organic compounds
Abstract Background: This study aimed to investigate changes in exhaled volatile organic compounds (VOCs) in divers exposed to hyperbaric air. Methods: A total of 17 adult divers underwent two sessions of hyperbaric air exposure at 30 m (400 kPa), separated by a one-week interval. In the first exposure, the divers were decompressed with hyperbaric air alone; in the second exposure, they breathed 100% oxygen for 30 min when decompressed to 18 m.
Cognitive risk during underwater exposure: from environmental stressors to assessment and context-aware monitoring
Abstract Underwater exposure imposes a distinctive cognitive burden because divers must maintain performance while environmental and physiological safety margins can change rapidly. Safe performance depends on attention, psychomotor speed, executive control, working memory, spatial orientation, metacognition, and decision-making, each of which may be influenced by pressure, breathing gases, respiratory load, immersion, thermal stress, fatigue, and individual susceptibility.
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