Hyun Woo Ryu on Muck Rack

Hyun Woo Ryu

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B7-H3 expression is associated with high PD-L1 expression in clear cell renal cell carcinoma and predicts poor prognosis - Diagnostic Pathology

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By Jung Lee, Yong Kim, Eun ji Kim, Chung Su Hwang, Jee Yeon Kim, Hyun Lee, Hyun Woo Ryu, Joo-Young Na
| Diagnostic Pathology
Background Clear cell Renal cell carcinoma (ccRCC) is an immunogenic tumor. B7 family members, such as CTLA-4, PD-1, and PD-L1, are the main components of immune checkpoints that regulate various immune responses. Specifically, B7-H3 regulates T cell-mediated immune responses against cancer.
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