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Articles by ICES Queen’s
Factors associated with early death from de novo metastatic breast cancer in Ontario, Canada
CMAJ October 19, 2026 198 (36) E1392-E1403; DOI: https://doi.org/10.1503/cmaj.260156 Article Figures & Tables Responses Metrics PDF Breast cancer affects 1 in 8 females during their lifetime, and 3000 patients are diagnosed with breast cancer annually in Ontario.1 De novo metastatic breast cancer is defined by the presence of distant metastatic disease at initial presentation and represents about 3% to 6% of all breast cancer diagnoses.
Risk of congenital anomalies among infants of patients with endometriosis: a population-based cohort study
CMAJ May 11, 2026 198 (18) E688-E697; DOI: https://doi.org/10.1503/cmaj.250439 Article Figures & Tables Responses Metrics PDF Increasing evidence exists of an association between endometriosis, a chronic inflammatory condition defined by the presence of endometrial-like tissue outside of the uterus, and adverse pregnancy outcomes, including pregnancy loss, preeclampsia, placental abruption, placenta previa, stillbirth, and preterm birth.1–3 Endometriosis can trigger inflammation and oxidative...
Trajectories of Health Care Contact Days for Patients With Stage IV Non-Small Cell Lung Cancer
Key Points Question What are the trajectories of contact days (days with health care contact outside the home) for patients with stage IV non–small cell lung cancer (NSCLC)? Findings In this cohort study including 5785 decedents with stage IV NSCLC, the median survival was 3.5 months and patients had spent 1 in 3 of those days with health care contact outside the home.
Implantable Hearing Devices in Ontario: A Population-Based Study of Access to Care and Access to Devices
Introduction: The prevalence of hearing loss in Canada is high, with many patients requiring implantable hearing devices (IHDs) as treatment for their disease severity. Despite this need, many eligible patients do not pursue these interventions. The objective of this study was to examine rates of IHD based on geographic location to understand locoregional variation in access to care. Study Design: This was a retrospective population-based cohort study.
Cancer Screening Disparities Before and After the COVID-19 Pandemic
Key Points Question Did preexisting disparities in cancer screening change after the COVID-19 pandemic? Findings In this cross-sectional study of 9 471 513 adults in Ontario, Canada, who were eligible for breast, cervical, and colorectal cancer screening before the COVID-19 pandemic, assessed at 2 time points, preexisting disparities in screening for people living in lower-income neighborhoods and for immigrants significantly widened for both breast and colorectal cancer screening.
Relational Continuity, Physician Payment, and Team-Based Primary Care in the Canadian Health Care System
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Virtual Care and Emergency Department Use During the COVID-19 Pandemic Among Patients of Family Physicians in Ontario, Canada
Key Points Question Do patients of family physicians who provide more virtual care have higher emergency department (ED) visit rates? Findings In this cross-sectional study of 13 820 family physicians with 12 951 063 patients in Ontario, Canada, we found that patients of physicians who provided a high percentage of virtual care during the first years of the COVID-19 pandemic did not have higher ED visits than patients of physicians who provided the lowest levels of virtual care.
Explaining the Variation in Surgical Practice for Differentiated Thyroid Cancer in Ontario, Canada
Original Investigation August 29, 2019 JAMA Otolaryngol Head Neck Surg. Published online August 29, 2019. doi:10.1001/jamaoto.2019.2304 Key Points Question What theory or concept may explain the wide variation in the surgical management of differentiated thyroid cancer?
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