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Igor Barković on Muck Rack

Igor Barković

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Articles

Vaccination provides superior in vivo recall capacity of SARS-CoV-2 specific memory CD8 T cells

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By Christoforos Dimitropoulos, Dora Gašparini, Jan Koster, Felix M. Wensveen, Inga Kavazović, Igor Barković, Niels A. Lemmermann
| Cell Reports Verified
Kavazović et al. compare SARS-CoV-2-specific memory CD8 T cells from people after infection, vaccination or both. Infection induces a more clonally diverse memory pool than vaccination, but these cells produce less TNF after in vivo recall. Subsequent vaccination negates differences, stressing the importance of boosting irrespective of antigenic history.
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