Ilhoon Jang

Capillary Driven Microfluidic Sequential Flow Device for Point-of-Need ELISA: COVID-19 Serology Testing Cody Carrell, Ilhoon Jang, Jeremy Link, James S Terry, Zachary Call, Yosita Panraska, Orawon Chailapakul, David S. Dandy, Brian Geiss and Charles Henry Abstract A capillary-driven microfluidic sequential flow device, designed for eventual at-home or doctor’s office use, was developed to perform an enzyme-linked immunosorbent assay (ELISA) for serology assays.

Simple manipulation of enzyme-linked immunosorbent assay (ELISA) using an automated microfluidic interface Among lateral flow immunoassay (LFIA) platforms, enzyme-based LFIAs use signal amplification to improve sensitivity. However, most enzyme-based LFIAs require multiple timed steps, complicating their use in point-of-care testing (POCT).

Flow control in a laminate capillary-driven microfluidic device Capillary-driven microfluidic devices are of significant interest for on-site analysis because they do not require external pumps and can be made from inexpensive materials. Among capillary-driven devices, those made from paper and polyester film are among the most common and have been used in a wide array of applications.