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Ingo Frommann

As seen in: Nature, Neurology Journal
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Articles by Ingo Frommann

Joint trajectories of brain atrophy, white matter hyperintensities and cognition quantify brain maintenance

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By Inga Menze, Jose Bernal, Rogier A. Kievit, Kumar Parijat Tripathi, Timo Kaleck, Renat Yakupov, Claudia Bartels, Katharina Buerger, Michaela Butryn, Peter Dechent, Michael Ewers, Klaus Fliessbach, Ingo Frommann, Wenzel Glanz, Daria Gref, Julian Hellmann-Regen, Stefan Hetzer, Enise I. Incesoy, Daniel Janowitz, Luca Kleineidam, Christoph Laske, Robert Perneczky, Oliver Peters, Josef Priller, Boris-Stephan Rauchmann, Ayda Rostamzadeh, Sandra Roeske, Klaus Scheffler, Anja Schneider, Sebastian Sodenkamp, Annika Spottke, Melina Stark, Stefan J. Teipel, Michael Wagner, Jens Wiltfang, Frank Jessen, Alfredo M. Ramirez, Alfredo Ramírez, Stefanie Schreiber, Emrah Düzel, Gabriel Ziegler, Slawek Altenstein, Maria Gemenetzi, Ingo Kiliman, Marie Theres Kronmüller, Debora Melo van Lent, Falk Lüsebrink, Lukas Preis, Björn-Hendrik Schott, Eike Jakob Spruth
| Nature Verified
Abstract Brain maintenance – the preservation of brain structure or function relevant to cognitive performance – remains challenging to quantify.
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Smartphone-based detection of subtle memory decline in prodromal Alzheimer’s disease

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By Sarah Polk, Lindsay Clark Verified, Luca Kleineidam, Wenzel Glanz, Michaela Butryn, Robert Perneczky, Katharina Buerger, Klaus Fliessbach, Christoph Laske, Annika Spottke, Anja Schneider, Jens Wiltfang, Stefan J. Teipel, Claudia Bartels, Ayda Rostamzadeh, Daniel Janowitz, Boris-Stephan Rauchmann, Frederic Brosseron, Michael Wagner, Ingo Frommann, Melina Stark, Matthias Schmid Verified, Björn H. Schott, Sterling Johnson, Frank Jessen, Emrah Düzel, David Berron, Kristin Basche, Ingo Kilimann, Sebastian Sodenkamp, Marie Coenjaerts
| Nature Verified
Abstract The slow progression of Alzheimer’s disease (AD) poses a challenge for the quantification of early disease-driven cognitive decline. Here, we show that frequently administered remote and unsupervised digital cognitive assessments can detect differences in cognitive decline within 30 weeks in early AD.
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Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS - Nature Medicine

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By Wiebke Möbius, Eckhard Mandelkow, Nicoleta Carmen Cosma, Josef Priller, Andrea Kuhn, Kathrin Brockmann, Daniel Alcolea, Juan Fortea, Alberto Lleó, Ingo Frommann, Lucas Bertram, Michael T. Heneka, Alfredo Ramirez, Alfredo Ramírez, Rudi Beschorner, Randall J. Bateman, Oriol Dols-Icardo, Gunter Hoglinger, Andreas Hermann, Sara Rubio-Guerra, Álvaro Carbayo, Sandra Roeske
| Nature Verified
Abstract Minimally invasive biomarkers are urgently needed to detect molecular pathology in frontotemporal dementia (FTD) and amyotrophic lateral sclerosis (ALS). Here, we show that plasma extracellular vesicles (EVs) contain quantifiable amounts of TDP-43 and full-length tau, which allow the quantification of 3-repeat (3R) and 4-repeat (4R) tau isoforms.
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Relevance of Minor Neuropsychological Deficits in Patients With Subjective Cognitive Decline

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By Steffen Wolfsgruber, Luca Kleineidam, Melina Stark, Ingo Frommann
| Neurology Journal Verified
Relevance of Minor Neuropsychological Deficits in Patients With Subjective Cognitive Decline Melina Stark, Steffen Wolfsgruber, Luca Kleineidam, Ingo Frommann, Slawek Altenstein, Claudia Bartels, Frederic Brosseron, Katharina Buerger, Lena Burow, Michaela Butryn, Michael Ewers, Klaus Fliessbach, Tatjana Gabelin, Wenzel Glanz, Doreen Goerss, Daria Gref, Niels Hansen, Michael T. Heneka, Petra Hinderer, Enise I Incesoy, Daniel Janowitz, Ingo Kilimann, Okka Kimmich, Christoph Laske, Matthias H.
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