Iris Lee on Muck Rack

Iris Lee

  • Technical Relationship Manager, Apple
Los Angeles
As seen in: Apple Podcasts, MSN, The New York Times, Nature, Reuters, Wiley, Wiley Online Library, Yahoo News, Los Angeles Times, SFGate and
Apple News Adjunct @USCAnnenberg
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Articles

U2AF1 mutations rescue deleterious exon skipping induced by KRAS mutations

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By David Walter, Katherine H. Cho, Smruthy Sivakumar, Daniel Denney, Iris Lee, Anders B. Dohlman, Jakob Heinz, Ethan Shurberg, Kevin Jiang Verified, Akansha Gupta, Garrett Frampton, Matthew Meyerson
| Nature Verified
Abstract The mechanisms by which mutations of splicing factor gene U2AF1 contribute to lung adenocarcinoma pathogenesis are not well understood. Here we used prime editing to modify the endogenous U2AF1 gene in lung adenocarcinoma cells and assessed the impact on alternative splicing. One specific KRAS mutation, G12S, led to skipping of KRAS exon 2 and generation of a nonfunctional KRAS transcript.
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Interactive narratives reveal the personalizing effect of agency on episodic memory

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By Xian Li, Savannah Born Verified, Iris Lee, Buddhika Bellana, Janice Chen, Nicole Kim Ni, Ria J. Gualano
| Nature Verified
Abstract Humans make choices that actively shape the trajectory of events in their lives. These choices rely on personal knowledge that can influence how these events are later remembered. We study how people’s memory for a naturalistic sequence of events is altered when their choices control the future. Participants read “choose-your-own-adventure” stories with full, partial, or no control over future events.
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Biodiversity and biogeography of the multi-kingdom cancer microbiome

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By Anders B. Dohlman, Robin Mjelle, Henry Wood, Kevin Jiang Verified, Alaina Shumate, Iris Lee, Gianmarco Piccinno, Garazi Serna, Abdul-Rakeem Yakubu, Paolo Nuciforo, Phil Quirke, Curtis Huttenhower, Nicola Segata, Matthew Meyerson
| Cell Press Verified
Keywords cancer microbiome biogeography decontamination multi-kingdom bacteria fungi viruses archaea mutation burden Get full text access Log in, subscribe or purchase for full access. References 1. Sender, R. ∙ Fuchs, S. ∙ Milo, R. Revised Estimates for the Number of Human and Bacteria Cells in the Body PLoS Biol. 2016; 14, e1002533 2. Berg, R.D. The indigenous gastrointestinal microflora Trends Microbiol. 1996; 4:430-435 3. Lloyd-Price, J. ∙ Mahurkar, A. ∙ Rahnavard, G. ...
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