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Isabelle Raymond Letron

As seen in: Cell Reports
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Articles

Leishmania infantum exploits the anti-ferroptosis effects of Nrf2 to escape cell death in macrophages

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By Marie Salon, Karin Santoni, Isabelle Raymond Letron, Lise Lefèvre
| Cell Reports Verified
Keywords ferroptosis-like process Leishmania infantum macrophage Nrf2 PGE2 ROS pharmacological treatment Research topic(s) CP: Immunology CP: Microbiology Introduction Leishmania species are intracellular protozoan parasites that cause multiple diseases, ranging from non-lethal cutaneous leishmaniasis to severe visceral disease, if left untreated.1 Leishmania infantum (L.i.) is one of the major parasite species associated with visceral leishmaniasis.2 Macrophages are the major myeloid-derived...
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