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Keywords Drosophila innate immunity horizontal gene transfer phage parasitoid cdtB Introduction Invertebrates and vertebrates deploy deeply homologous innate immune pathways against microbial pathogens that are well understood.1,2,3,4,5,6 However, less is known about the evolution of innate immune pathways against metazoan parasites7 (macroparasites) that can cause chronic infections8 and facilitate Red Queen-like coevolutionary dynamics.7,9,10,11 Indeed, the local diversity of parasitic...
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