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Oral chronic graft-versus-host disease
Abstract Background Long-term survivors of allogeneic hematopoietic cell transplantation will increasingly seek care from dental providers. Methods The authors highlight the importance of minimizing oral symptoms and complications associated with oral chronic graft-versus-host-disease (cGVHD). Results Chronic GVHD is the result of an immune response of donor-derived cells against recipient tissues. Oral cGVHD can affect the mucosa and damage salivary glands and cause sclerotic changes.
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