Izzatulo Sobitov on Muck Rack

Izzatulo Sobitov

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Articles

A modular method for high-throughput measurement of ion channel currents in cardiac myocytes

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By Fitzwilliam Seibertz, Alexey Alekseev, Thomas Mager, Constanze Schmidt, Niels Voigt, Izzatulo Sobitov, Marcus L. Gerloff, Aiste Liutkute, Funsho E. Fakuade
| Nature Verified
Abstract The patch-clamp technique offers unparalleled insight into the electrical and biophysical behavior of excitable cells. However, it is a slow and low-throughput method that typically requires cells to be measured one by one. Human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CM) are regularly subjected to this technique to unravel the molecular mechanisms of cardiac diseases.
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