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J. Edward van Veen on Muck Rack

J. Edward van Veen

As seen in: Cell Press
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Articles

A bifunctional optical reporter for tracking estrogen response dynamics in neurons

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By Alexandra L. Cara, Eartha Mae Guthman, Aarya Mishra, Alexanne L. Hall, Sae Yokoyama, Hannah N. Azadi, Ian Gregg, Rosalizbeth M. Martinez, Norma Sandoval, Krisha Aghi, Kiran K Soma, Stephanie M. Correa, Annegret L. Falkner, J. Edward van Veen
| Cell Press Verified
Keywords hormone dynamics estrogen signaling estrogen receptor alpha (ERα) fiber photometry in vivo imaging viral transcriptional reporter gene expression hypothalamus neuroendocrinology genetically encoded reporter Introduction Estrogens are highly dynamic hormones, and their changing levels drive striking transformations in both physiology and behavior.1,2,3,4,5,6,7,8 It is currently difficult to track their effects continuously in vivo, hampering progress in understanding the dynamic role...
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