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J. Yingling

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ALK5 Kinase Inhibitors in Drug Discovery: Structural Insights and Therapeutic Applications

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By K. Garber, J. Yingling
| ScienceDirect Verified
Introduction Transforming growth factor beta (TGF-β) is a promising target for the treatment of a variety of heterogeneous diseases, including cancer and fibrosis [1], [2]. TGF-β belongs to TGF-β superfamily of proteins that includes TGF-β1, TGF-β2, TGF-β3, inhibins, and activins [3].
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