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Jack Feldman

As seen in: IMDb, Nature, Frontiers, The Mercury News, The Universe, BioRxiv, GameRant, Cell Press, JNeurosci, The Daily Gazette and
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Articles

LA100’s Ambition Is Clear. Its Cost to Ratepayers Is Not

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By Jack Feldman
| CityWatchLA Verified
MY VOICE - Electric bills across Los Angeles are rising, and many ratepayers are asking why. Behind those increases is LA100, the City’s plan to move to a carbon free electric system by 2035. The goal is ambitious and well intentioned. The cost, however, is very large, arrives early, and is not well understood by the public. Most Angelenos support cleaner energy and a modern electric grid.
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Proof of concept for high-dose Cannabidiol pretreatment to antagonize opioid induced persistent apnea in mice

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By Jack Feldman
| Frontiers
Department of Neurobiology, David Geffen School of Medicine, UCLA, Los Angeles, CA, United States Background: Opioid related fatalities remain a public health crisis in the US. Currently, the only way to restore breathing following an opioid induced persistent apnea is with the administration of the opioid antagonist naloxone, but it also reverses analgesia, euphoria, and induces precipitated withdrawal in opioid dependent individuals.
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Sigh generation in preBötzinger complex

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By Yan Cui, Evgeny Bondarenko, Delia N Chiu, Jack Feldman
| eLife
eLife Assessment This valuable study by Cui et al. investigates mechanisms generating sighs, which are crucial for respiratory function and linked to emotional states. Utilizing advanced methods in mice, they provide solid evidence that increased excitability in specific preBötzinger complex neuronal subpopulations expressing Neuromedin B receptors, gastrin-releasing peptide receptors, or somatostatin can induce sigh-like large amplitude inspirations.
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