Jack Kay Clegg

One-pot synthesis of azepine spiro[4.6]-γ-lactams by a Hantzsch-type reaction A facile route to spiro-γ-lactams containing fused seven- and five-membered rings is showcased here in a multicomponent reaction harnessing glycine. Four spiro-γ-lactams were characterised, including by X-ray diffraction techniques, showing them to be trapped unstable intermediates of the Strecker degradation.

Self-assembled Co(II) and Co(III) [M2L3] helicates and [M4L6] tetrahedra from an unsymmetrical quaterpyridine ligand In order to bind guest molecules with exquisite selectivity, biological host molecules often employ low symmetry binding pockets. The majority of metallosupramolecular assemblies, however, rely on symmetrical ligands to form high-symmetry assemblies that enclosing similiarly symmetrical cavities.

Co-existence of Five- and Six-Coordinate Iron(II) Species Captured in a Geometrically Strained Spin-Crossover Hofmann Framework Luonan Xu, Zixi Xie, Katrina A Zenere, Jack Kay Clegg, Elise Kenny, Nicole J Rijs, Guy N. L. Jameson, Ben Powell, Cameron J. Kepert and Suzanne M. Neville Abstract Inclusion of an angular bridging ligand, 4,2′:6′,4′′-terpyridine (TPy), into a Hofmann-type framework produces an irregular network in which six- and five-coordinate FeII species co-exist.