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Jaël Rut Senn on Muck Rack

Jaël Rut Senn

As seen in: Cell Metabolism
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Beta2-adrenergic stimulation by fenoterol increases energy expenditure without activating human brown adipose tissue

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By Anand Sharma, Carla Horvath, Claudia Irene Maushart, Adhideb Ghosh, Kirsi A. Virtanen, Tobias Fromme, Alin Chirindel, Damian Wild, Søren Nielsen, Christian Wolfrum, Matthias Johannes Betz, Laila Maria Füchtbauer, Jaël Rut Senn, Carole Stéphanie Baumann, Anninja Lea Isenrich, Taylah Lea Gaynor, Rahel Schläfli
| Cell Metabolism Verified
Introduction Brown adipose tissue (BAT) can directly convert chemical energy into heat by uncoupling the respiratory electron transport chain from ATP synthesis in mitochondria.1 While long known for its importance to maintaining core body temperature in human infants, its presence and activity in adult humans were unequivocally demonstrated only in 2009.2,3,4 Active BAT is associated with a lower likelihood of obesity and metabolic disease such as type 2 diabetes or cardiovascular disease.5...
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