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Jaesoo Jung on Muck Rack

Jaesoo Jung

As seen in: Cell Reports
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Articles

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By Susmita Sarkar, Jhon R. Enterina, Laura Streith, Jaesoo Jung, Britni M. Arlian, Sarah Meyer, Hiromu Takematsu, Changchun Xiao, Troy A. Baldwin, Lars Nitschke, James C. Paulson, Matthew S. Macauley, Jhon R. Enterina, Laura Streith, Jaesoo Jung, Mark J. Shlomchick
| Cell Reports Verified
Highlights • A mouse model (CMAHON) is made to test a role for altered glycosylation in the GC • CMAHON display a CD22-dependent defective GC response • Altered glycosylation in the GC affects the ability of CD22 to regulate the BCR • Altered glycosylation/CD22 play a role in antigen processing, survival, and selection Summary Germinal centers (GCs) are essential for antibody affinity maturation.
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