James Bagley on Muck Rack

James Bagley

As seen in: BBC, Color Research & Application, Nature, The Daily Mirror, Wiley Online Library, Daily Express, ScienceDirect, Scottish Daily Record, Des Moines Register, Surrey Advertiser and
Senior news and communications officer at Three Rivers District Council. Former Local Democracy Reporter for the Slough & Royal Borough Observer.
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Articles

Ergothioneine controls mitochondrial function and exercise performance via direct activation of MPST

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By Kevin A. Murach, James Bagley, Nguyen NGUYEN, NGuyen nguyen, Giovanni Rigoni
| ScienceDirect
Exercise training can prevent and ameliorate many chronic diseases.1,2 Consistent with this, exercise capacity is a powerful predictor of mortality, with an increase in each one metabolic equivalent (1-MET) exercise capacity conferring a 12% improvement in survival.3 Thus, it is of great interest to identify key regulators of the beneficial effects of exercise.
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Gut check: Unveiling the influence of acute exercise on the gut microbiota

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By Gregory J. Grosicki, Sean Langan, James Bagley, Andrew Galpin
| Wiley Online Library
1 INTRODUCTION The human body is inhabited by a vast number of microorganisms living in complex ecological communities that influence human physiology (Dekaboruah et al., 2020). While these microorganisms, collectively known as the microbiota, are found in all body cavities and on human surfaces, the vast majority of the microbiota resides in the gastrointestinal tract (i.e., gut microbiota) (Sender et al., 2016).
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Screening non-conventional yeasts for acid tolerance and engineering Pichia occidentalis for production of muconic acid - Nature Communications

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By James Bagley, Kaspar Kevvai, Malcolm Whiteway
| Nature
Abstract Saccharomyces cerevisiae is a workhorse of industrial biotechnology owing to the organism’s prominence in alcohol fermentation and the suite of sophisticated genetic tools available to manipulate its metabolism. However, S. cerevisiae is not suited to overproduce many bulk bioproducts, as toxicity constrains production at high titers. Here, we employ a high-throughput assay to screen 108 publicly accessible yeast strains for tolerance to 20 g L−1 adipic acid (AA), a nylon precursor.
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