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Articles by James E San
Design of SARS-CoV-2 RBD Immunogens to Focus Immune Responses Towards Conserved Coronavirus Epitopes
Abstract SARS-CoV-2 continues to evolve, with new variants emerging that evade pre-existing immunity and limit the efficacy of existing vaccines. One approach towards developing superior, variant-proof vaccines is to engineer immunogens that preferentially elicit antibodies with broad cross-reactivity against SARS-CoV-2 and its variants by targeting conserved epitopes on spike.
An Oxford Nanopore Technology-Based Hepatitis B Virus Sequencing Protocol Suitable for Genomic Surveillance Within Clinical Diagnostic Settings
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An Oxford Nanopore Technology-Based Hepatitis B Virus Sequencing Protocol Suitable For Genomic Surveillance Within Clinical Diagnostic Settings
Preprint Article Version 1 This version is not peer-reviewed Version 1 : Received: 2 October 2024 / Approved: 3 October 2024 / Online: 4 October 2024 (04:13:58 CEST) Tshiabuila, D.; Choga, W.; San, J. E.; Maponga, T. G.; Preiser, W.; Van Zyl, G. U.; Moir, M.; Van Wyk, S.; Giandhari, J.; Pillay, S.; Anyaneji, U. J.; Lessells, R. J.; Naidoo, Y.; Sanko, T.; Wilkinson, E.; Tegally, H.; Baxter, C.; Martin, D. P.; de Oliveira, T.
SeqPanther: Sequence manipulation and mutation statistics toolset
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Emergence of SARS-CoV-2 Omicron lineages BA.4 and BA.5 in South Africa - Nature Medicine
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Abstract Three lineages (BA.1, BA.2 and BA.3) of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern predominantly drove South Africa’s fourth Coronavirus Disease 2019 (COVID-19) wave. We have now identified two new lineages, BA.4 and BA.5, responsible for a fifth wave of infections.
By Josie Everatt, Marta Giovanetti, Cathrine Scheepers, Daniel G. Amoako, Cheryl Baxter, Christian L. Althaus, Richard Lessells, Tongai Maponga, Tomasz Janusz Sanko, James E San, Graeme Dor, Wolfgang Preiser, Marietjie Venter, Áine O’Toole, Thomas Peacock, Cornelius Roemer, Carolyn Williamson, Oliver G. Pybus, Jinal N. Bhiman, Allison Glass, Andrew Rambaut, Tulio de Oliveira
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Nature
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The evolving SARS-CoV-2 epidemic in Africa: Insights from rapidly expanding genomic surveillance.
Houriiyah Tegally, James E. San, View ORCID ProfileMatthew Cotten, Bryan Tegomoh, Gerald Mboowa, Darren P. Martin, Cheryl Baxter, Monika Moir, Arnold Lambisia, Amadou Diallo, Daniel G. Amoako, Moussa M. Diagne, Abay Sisay, Abdel-Rahman N. Zekri, Abdelhamid Barakat, Abdou Salam Gueye, Abdoul K. Sangare, Abdoul-Salam Ouedraogo, Abdourahmane SOW, Abdualmoniem O. Musa, Abdul K. Sesay, Adamou LAGARE, Adedotun-Sulaiman Kemi, Aden Elmi Abar, Adeniji A. Johnson, Adeola Fowotade, Adewumi M. Olubusuyi, Adeyemi O.
A year of genomic surveillance reveals how the SARS-CoV-2 pandemic unfolded in Africa
View ORCID ProfileEduan Wilkinson, Marta Giovanetti, Houriiyah Tegally, James E San, Richard Lessels, Diego Cuadros, Darren P Martin, Abdel-Rahman N Zekri, Abdoul Sangare, Abdoul Salam Ouedraogo, Abdul K Sesay, Adnene Hammami, Adrienne A Amuri, Ahmad Sayed, Ahmed Rebai, Aida Elargoubi, Alpha K Keita, Amadou A Sall, Amadou Kone, Amal Souissi, Ana V Gutierrez, Andrew Page, Arnold Lambisia, Arash Iranzadeh, Augustina Sylverken, Azeddine Ibrahimi, Bourema Kouriba, Bronwyn Kleinhans, Beatrice...
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