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Houriiyah Tegally

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Articles

Global approaches to infectious disease surveillance and modeling

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By Mark P Khurana, Joseph Tsui, Bernardo Gutiérrez, Ayush Chopra, Neil Scheidwasser, Serina Chang, David A. Duchêne, Cathal Mills, Rhys Inward, Benjamin Reddy, John Brittain, Abhishek Dasgupta, James Sheldon, George Githinji, John S. Brownstein, Mélodie Monod, Luca Ferretti, Sivan Bershan, Simon Tietze, Leo Ferres, Silvia Argimon, Timothy J. Dallman, Etien Luc Koua, Oliver Ratmann, Simon Cauchemez, Lauren Meyers, Lili Su, Alessandro Vespignani, Paul Pronyk, Áine O’Toole, Andrew Rambaut, Nicholas J. Loman, Edward Holmes, Seth Flaxman, Nicola Mulder, Oliver Morgan, Houriiyah Tegally, Manuel Gomez-Rodriguez, Nigel Shadbolt, Christian T. Happi, Meera A Chand, Sofonias K. Tessema, Placide Mbala-Kingebeni, Marc A. Suchard, Oliver G. Pybus, Samuel V. Scarpino, Samir Bhatt, Moritz Kraemer
| Nature Verified
Abstract Human mobility, climate change and demographic trends increase the risk of pathogen spillover and expansion. Data that can inform our responses to outbreaks have increased in availability and volume, but access to highly confidential outbreak data and commercially sensitive contextual information remains difficult.
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Dynamics and ecology of a multistage expansion of Oropouche virus in Brazil

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By Houriiyah Tegally, Simon Dellicour, Jenicca Poongavanan, Carla Mavian, Graeme Dor, Vagner Fonseca, Massimiliano S. Tagliamonte, Marcel Dunaiski, Monika Moir, Eduan Wilkinson, Edward C. Holmes, Cheryl Baxter, Richard Lessells, Moritz Kraemer, José Lourenço, Tulio de Oliveira, Marta Giovanetti, Livia C. V. Frutuoso
| Nature Verified
Abstract In March 2024, Brazil reported an unprecedented Oropouche fever outbreak, driven by the emergence of a reassortant lineage of the Oropouche virus (OROV) expanding beyond the Amazon Basin. To investigate the expansion dynamics of OROV, we implemented complementary phylogeographic and ecological niche modelling approaches that aimed to characterize the environmental factors associated with the range expansion and the risk of local circulation, respectively.
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Tracing the spatial origins and spread of SARS-CoV-2 Omicron lineages in South Africa - Nature Communications

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By Eduan Wilkinson, Monika Moir, Martin M Nyaga, Tongai Maponga, Oluwakemi Laguda-Akingba, Cheryl Baxter, Nei-yuan Hsiao, Wolfgang Preiser, Jinal N. Bhiman, Marietjie Venter, Nicole Wolter, Carolyn Williamson, Anne von Gottberg, Richard Lessells, Houriiyah Tegally
| Nature Verified
Abstract Since November 2021, five genetically distinct SARS-CoV-2 Omicron lineages (BA.1–BA.5) are believed to have emerged in southern Africa, with four (BA.1, BA.2, BA.4, and BA.5) spreading globally and collectively dominating SARS-CoV-2 diversity. In 2023, BA.2.86, a highly divergent BA.2 lineage that rose to prominence worldwide, was first detected in Israel and Denmark, but the subsequent diversity of South African sequences suggests it too emerged in the region.
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