Jan-Bernd Stukenborg

To the Editor: Acute lymphoblastic leukaemia (ALL) in children and adolescents may affect the testes at diagnosis or relapse. Highly aggressive treatments such as haematopoietic stem cell transplantation are recommended for early testicular relapse and T-cell ALL. Patients with late isolated testicular relapse of B-cell ALL can generally be cured by salvage chemotherapy combined with scrotal irradiation or orchiectomy [1].

Jan-Bernd Stukenborg1 and Christine Wyns2 1NORDFERTIL Research Lab Stockholm, Childhood Cancer Research Unit, Department of Women’s and Children’s Health, Karolinska Institutet and Karolinska University Hospital, Solna, Sweden 2Cliniques Universitaires Saint-Luc, Université Catholique de Louvain, Brussels, Belgium Abstract Genetic parenthood following cancer therapy is considered to be a major factor of quality of life.

Genetic parenthood following cancer therapy is considered to be a major factor of quality of life. Given the rising proportion of patients surviving cancer due to improved therapeutic protocols, it is an issue of growing importance. Hence, the efforts to preserve fertility have motivated researchers to develop options for the paediatric population facing fertility-threatening cancer therapies.