Janesh K. Gupta

Abstract : Whilst S100P has been shown to be a marker for carcinogenesis, we have shown, in non-physio-pathological states, that its expression promotes trophoblast motility and invasion but the mechanisms explaining these cellular processes are unknown.

This is an early access version, the complete PDF, HTML, and XML versions will be available soon. Open AccessArticle by Maral E. A. Tabrizi 1, Janesh K. Gupta 2,3 and Stephane R. Gross 1,* 1 School of Life and Health Sciences, Aston University, Birmingham B4 7ET, UK 2 Institute of Metabolism and Systems Research, University of Birmingham, Birmingham B15 2TT, UK 3 Fetal Medicine Centre, Birmingham Women’s NHS Foundation Trust, Birmingham B15 2TT, UK * Author to whom correspondence should be addressed.

In recent years, numerous studies have been conducted, which have demonstrated the efficacy and safety of using mechanical methods for the induction of labor with an unfavorable Bishop Score (BS ≤ 6). Mechanical methods work by stimulating the endogenous production of prostaglandins (PG) by stretching the amnio-chorionic membranes and myometrial cells.