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Janet Rubin

As seen in: Medscape, The Journal of Biological Chemistry
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Articles by Janet Rubin

Lumbar Scoliosis and Osteoporosis in Postmenopausal Women

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By Janet Rubin, Rebecca J. Cleveland, David Hu, Alexander Padovano
| Medscape Verified
Abstract and Introduction Abstract Context: The contribution of lumbar scoliosis to osteoporosis is unknown. Objective: This work aimed to determine the prevalence and relationship of lumbar scoliosis to osteoporosis in aging women. Methods: A cross-sectional analysis used dual-energy x-ray absorptiometry (DXA) scans of randomly selected groups of postmenopausal women (64-68, 74–78, and 84–88 years; N = 300 each) in a university teaching hospital from 2014 to 2019.
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Epigenetic Plasticity Drives Adipogenic and Osteogenic Differentiation of Marrow-derived Mesenchymal Stem Cells

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By Mark Meyer, Nancy A. Benkusky, Buer Sen, Janet Rubin
| The Journal of Biological Chemistry Verified
Terminal differentiation of multipotent stem cells is achieved through a coordinated cascade of activated transcription factors and epigenetic modifications that drive gene transcription responsible for unique cell fate. Within the mesenchymal lineage, factors such as RUNX2 and PPARγ are indispensable for osteogenesis and adipogenesis, respectively.
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Epigenetic Plasticity Drives Adipogenic and Osteogenic Differentiation of Marrow-Derived Mesenchymal Stem Cells

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By Mark Meyer, J. Wesley Pike, Nancy A. Benkusky, Buer Sen, Janet Rubin
| The Journal of Biological Chemistry Verified
Terminal differentiation of multipotent stem cells is achieved through a coordinated cascade of activated transcription factors and epigenetic modifications that drive gene transcription responsible for unique cell fate. Within the mesenchymal lineage, factors such as RUNX2 and PPARγ are indispensable for osteogenesis and adipogenesis, respectively.
Open in Who Shared Issue with article?
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