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A randomized, placebo-controlled study of chitosan gel for the treatment of chronic diabetic foot ulcers (the CHITOWOUND study)
Diabetic foot ulcers (DFUs) are the leading cause of lower-limb amputations. Some studies indicate that chitosan products may have potential wound healing properties, but the efficacy and safety in DFUs treatment is not well studied. Efficacy and safety of a chitosan-based gel in treatment of DFUs were evaluated. The chitosan-based gel accelerated the healing process of DFUs and significantly improved wound state after 10 weeks and showed a safety profile comparable to placebo.
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