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Jasmin Bartl on Muck Rack

Jasmin Bartl

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Articles

Berzosertib enhances the sensitivity of pediatric diffuse midline glioma H3K27-altered cells to radiotherapy

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By Daniel Picard, Sarah Afshar, Michelle Monje, Eric Raabe, Arndt Borkhardt, Guido Reifenberger, Nicole Dünker, Maike Busch, David Pauck, Nan Qin, Johann Matschke, Verena Jendrossek, Nikita Gorainow, Felix Sander, Marvin Christopher Frölich, Katharina Eul, Julia Asche, Jasmin Bartl
| Nature Verified
Abstract Diffuse midline glioma H3K27M-altered (DMG) remains a fatal pediatric brain cancer driven by a global loss of histone H3K27 trimethylation. Radiotherapy comprises the most important treatment modality and significantly improves overall survival. Novel therapeutic strategies for DMG patients without or with radiotherapy are urgently needed. Here, we aimed to gain insights into potential radiation response modulators.
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