Sarah Afshar

Abstract Diffuse midline glioma H3K27M-altered (DMG) remains a fatal pediatric brain cancer driven by a global loss of histone H3K27 trimethylation. Radiotherapy comprises the most important treatment modality and significantly improves overall survival. Novel therapeutic strategies for DMG patients without or with radiotherapy are urgently needed. Here, we aimed to gain insights into potential radiation response modulators.

1. Introduction Mineral fertilizers represent an essential component of global agriculture, but their overuse can negatively affect soil health and biodiversity [1]. Currently, attempts are being made to reduce the use of mineral fertilizers, while maintaining the same yields and quality of the final agricultural product [2].

Imagine waking up one day, thinking your day is going to be great. And in a sudden second, all of that changed. This happened to Michele Barton on April 22, 2012 when she received the sudden news that her son Tanner was dead. In the early morning of the day, Barton received a call hours after her son was found. With so many questions left unanswered, she is still trying to find the answers to what happened on that cold Spring night in Kokomo, Indiana.