Jason Shulman

You are already at the latest version Consensus sequences at sites such as exon-intron boundaries or branch points are succinctly displayed with sequence logos.

I write as a resident of Colorado, where every drop of the river matters to our farms, families, and future. I have no fiduciary interest in water. I don’t own land around it, nor any water rights attached to it. But, simply put, I like to drink water to survive so its supply in the very dry American West has always interested me. Particularly the Colorado River and the millions of us who depend on it. The Colorado River is the lifeline of the American West, but it is dangerously over‑appropriated.

Advances in microarray and sequencing technologies have made possible the interrogation of biological processes at increasing levels of complexity. The underlying biomolecular networks contain large numbers of nodes, yet interactions within the networks are not known precisely. In the absence of accurate models, one may inquire if it is possible to find relationships between the states of such networks under external changes, and in particular, if such relationships can be model-independent.