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Jayce Doose on Muck Rack

Jayce Doose

As seen in: Brain Stimulation
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Articles

TMS-induced modulation of brain networks and its associations to rTMS treatment for depression: a concurrent fMRI-EEG-TMS study

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By Hengda He, Xiaoxiao Sun, Jayce Doose, Josef Faller
| Brain Stimulation Verified
• Introduction Transcranial magnetic stimulation (TMS) over the left dorsolateral prefrontal cortex (L-DLPFC) is a Food and Drug Administration-approved treatment for depression. TMS therapy has demonstrated efficacy and safety in the treatment of patients with treatment-resistant depression (TRD)1,2. However, the mechanism of action underlying the therapeutic effects of TMS is still unclear.
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Daily prefrontal closed-loop repetitive transcranial magnetic stimulation (rTMS) produces progressive EEG quasi-alpha phase entrainment in depressed adults

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By Xiaoxiao Sun, Josef Faller, Jayce Doose, James R. Mclntosh
| Brain Stimulation Verified
Highlights • EEG-triggered repetitive TMS (rTMS) was applied over DLPFC either synchronously or asynchronous timed to an individual's quasi-alpha oscillation phase for patients' undergoing treatment for major depressive disorder. • Patients that received synchronous rTMS showed increased entrainment over sessions across days and decreased phase difference relative to the optimal phase for the therapeutic target (anterior cingulate).
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