Jayesh Kumar Sevak on Muck Rack

Jayesh Kumar Sevak

As seen in: Nature, Wiley Online Library, Taylor & Francis Online
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Articles

Radiofrequency radiation-induced changes in Leydig cell function

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By Pooja Jangid, Umesh Rai, Jayesh Kumar Sevak, Ravi Ranjan, Sanjay Singh Verified, Rajeev Singh
| Nature Verified
Abstract Radiofrequency radiation, emitted from commonly used wireless communication devices, has been implicated in disrupting cellular homeostasis; however, its effects on testicular somatic cells such as Leydig cells remain poorly understood. To address this, the present study investigated the frequency- and time-specific effects of RFR on cellular morphology, proliferation, and cell cycle dynamics in TM3 Leydig cells.
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Differential Methylation Patterns Predict HBsAg Seroconversion in Hepatitis B Virus Reactivation Patients

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By Jayesh Kumar Sevak, Mojahidul islam, Gayantika Verma, Anoushka Saxena
| Taylor & Francis Online
ABSTRACT Background Hepatitis B virus (HBV) modulates immune epigenetic landscape. Therefore, we investigated immune epigenetic landscape in HBsAg seroconverters and non-seroconverters. Methods Sixteen rHBV patients including seroconverters (SC, n = 7) and non-seroconverters (NSC, n = 9) at baseline and week 24 were recruited. Age matched naïve chronic hepatitis B patients (nCHBV, n = 7) and healthy controls (HC, n = 6) were also included.
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Epigenetic mediated functional reprogramming of immune cells leads to HBsAg seroconversion in Hepatitis B Virus Reactivation patients

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By Jayesh Kumar Sevak, Mojahidul islam, Anoushka Saxena, Gayantika Verma
| biorxiv.org
Abstract Background: Hepatitis B virus (HBV) modulates epigenetic landscape by epigenetic regulators. HBsAg seroconversion is possible with immune activation, therefore we aimed to investigate epigenetic modulation in HBV reactivation (rHBV) for viral clearance and seroconversion.
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