J.C. Barrett

Under a Creative Commons license open access Key words Lueyang black-boned chicken eggshell color SLCO1B3 L*a*b color space association analysis INTRODUCTION Eggshell color is an intuitive external trait affecting consumer acceptance (Zeng et al., 2022). Different countries have different preferences for eggshell color. For example, white eggs are preferred in Japan and North America, but pink and brown eggs are more popular in China (Berkhoff et al., 2020;Yang, 2021).

HIGHLIGHTS • We investigated if there is a role for tumor testing in HER2-negative metastatic breast cancer with germline BRCA mutations • Tumor testing was able to detect known germline BRCA mutations, with 99% concordance for tumor tissue and blood • Homologous recombination deficiency (HRD) scores were mostly high and gene-specific loss of heterozygosity (LOH) was >90% • Olaparib activity was seen in the few tumors with low HRD scores or lacking LOH • Additional measurement of genome...