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Jeffrey Bruce on Muck Rack

Jeffrey Bruce

As seen in: Color Research & Application, Nature, MDPI, Medscape, The Atlanta Journal-Constitution, New Atlas, BioRxiv, Cell Press, Arizona Daily Star, HemOnc Today

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A review of Jessica Harper's performance in Suspiria.

Articles

Longitudinal validation of ENLIGHT, an AI predictor of immunotherapy response and resistance, in pan-cancer cohorts

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By Changsu Park, Gal Dinstag, Carlos Lopes, Scott Strum, Jeffrey Bruce, Omer Tirosh, Saugato Rahman Dhruba, Danh-Tai Hoang, Tuvik Beker, Eldad D. Shulman, Anna Spreafico, Philippe Bédard, Sofia Genta, Albiruni R. Abdul Razak, Eytan Ruppin, Ranit Aharonov, Lillian L. Siu
| Nature Verified
Abstract Artificial intelligence (AI) algorithms such as ENLIGHT and DeepPT represent promising approaches to identify predictive biomarkers for immune checkpoint blockade (ICB). Evaluation of ICB response prediction throughout the span of ICB treatment provides a dynamic perspective of a biomarker’s predictive value. A post-hoc analysis of two pan-cancer trials of patients receiving ICB was performed. Samples were available from the pre-ICB, on-ICB and post-progression timepoints.
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Emerging roles of ferroptosis in modulating the immune landscape of glial tumours

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By Michael G Argenziano, Taruna V. Neelakantan, Oluwaseyi Adeuyan, Dominique Higgins, Jeffrey Bruce, Betty Kim, Athanassios Dovas, Peter Canoll, Michael Lim, Brent R. Stockwell, Matei A Banu, Colin Sperring
| Nature Verified
Abstract The brain offers a unique environment for cancer, with limited access to nutrients and highly regulated immune surveillance. Here we explore the role of ferroptosis, a form of metabolically regulated cell death driven by iron-mediated lipid peroxidation, in shaping immune-cell composition and function in glial tumours. We review the complex metabolic crosstalk between cell populations regulating ferroptosis in the glioma milieu.
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20th anniversary of the Annual Neurosurgery Charity Softball Tournament: an evolving tradition

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By Nicholas B. Dadario, Jeffrey Bruce, Ricardo J Komotar
| thejns.org
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