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Jeffrey E. Barrick on Muck Rack

Jeffrey E. Barrick

As seen in: Nature, PLOS Biology, PLOS ONE, PNAS, ACS Publications, BioRxiv, ASM Journals
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Articles

Genetic Biosensor for Optimizing Double-Stranded RNA Production by Bacteria Click to copy article link Article link copied!

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By Lucio Navarro-Escalante, Anthony J. VanDieren, Jeffrey E. Barrick
| ACS Publications
Several methods have been developed to detect and visualize double-stranded RNA (dsRNA) in cells and tissues, including immunofluorescence assays and the use of dsRNA-binding domains fused to fluorescent proteins. (1−3) These tools have been primarily designed to detect viral dsRNA molecules in eukaryotic cells for studying and diagnosing infections of mammalian and plant viruses. (4,5) They are not suitable for the in vivo quantification of dsRNA molecules in prokaryotic cells.
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Symbiotic bacteria produce non-lytic vesicles with nucleic acid cargo

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By Nurila Kambar, Yulin Song, Carmen Herrera, Sean Leonard, Jeffrey E. Barrick, M. Stephen Trent, Nancy Moran, Cecilia Gontijo Leal, Cecília G. Leal, Max Baliga
| Nature Verified
Abstract Symbiotic bacteria in the gut have an important physiological impact on their hosts, but the mechanisms that underlie the exchange of molecular signals remain poorly understood. Membrane vesicles have been suggested to mediate the direct exchange of cytoplasmic content like nucleic acids (NAs), but their study is complicated by conflicting and imprecise reports of their type and composition.
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Genome Evolution of Acinetobacter baylyi ADP1 During Laboratory Domestication: Acquired Mutations Impact Competence and Metabolism

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By Isaac Gifford, Jeffrey E. Barrick, Meghna Vergis
| BioRxiv
Abstract The bacterium Acinetobacter baylyi is a model organism known for its extreme natural competence and metabolic versatility. It is capable of transforming environmental DNA at a high frequency across all growth phases. The type strain ADP1 was created by random mutagenesis of a precursor strain, BD4, to prevent it from forming cell chains in culture. ADP1 has since been distributed between research groups over several decades and acquired subsequent mutations during this time.
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