Jenifer S. Davis on Muck Rack

Jenifer S. Davis

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Articles

Signet ring cell colorectal cancer: genomic insights into a rare subpopulation of colorectal adenocarcinoma

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By Krittiya Korphaisarn, Van Morris, Michael J. Overman, Jenifer S. Davis
| Nature Verified
Abstract Background Signet ring cell carcinoma (SRCC) is a rare subtype of colorectal cancer (CRC). The aim of this study was to characterise the genomic alterations and outcomes of SRCC. Methods Medical records of metastatic CRC (mCRC) patients whose tumours were evaluated by NGS analysis were reviewed. SC-mCRC were classified into two groups: SRCC (>50% signet ring cells) and adenocarcinoma (AC) with SC component (≤50% signet ring cells).
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