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Van Morris

Mount Washington
As seen in: Nature, MDPI, The BMJ, JAMA Oncology, Medscape, Cell Press, HemOnc Today, Grimsby Live, Texas Medical Center, ONCOLOGY journal and
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Articles

Spatial multi-omics landscape of colorectal cancer macro- and micrometastases

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By Yang Liu, Akshaya Jadhav, Yuwen Pan, Jianlong Liao, Isha Khanduri, Yunhe Liu, Riham Katkhuda, Wei Lu, Kyung Serk Cho, Zhimin Tong, Tieling Zhou, Kangyu Lin, Baohua Sun, Mei Jiang, Sharia Hernandez, Patrick Brennan, Guangsheng Pei, Kai Yu, Yibo Dai, Tian Ren Chu, Fuduan Peng, Ling Xia, Youming Guo, Alicia Mejia, Sean Barnes, Ou Shi, Alaa Mohamed, Natalie Fowlkes, Timothy Newhook, Yun Shin Chun, Van Morris, David G. Menter, Dadi Jiang, John Paul Shen, Ryan Sun, Jean-Nicolas Vauthey, Ruoyan Li, Humam Kadara, Scott Kopetz, Linghua Wang, Dipen M. Maru, Saxon Rodriguez, Shreeya Indulkar, Luisa M. Solis Soto
| Cell Press Verified
Introduction While early detection through screening has significantly reduced the incidence of localized colorectal cancer (CRC),1 limited understanding of the biological mechanisms driving colorectal metastasis remains a major barrier to improving long-term survival.
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IL1R1 blockade augments CD40 agonist mediated immunity in pancreatic cancer

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By Akash R Boda, Irfan N Bandey, Saikat Chowdhury, Sadhna Aggarwal, Venugopalareddy Mekala, Natalie Fowlkes, Amanda Anderson, Jason Roszik, Michael Curran, Van Morris, Scott Kopetz, Manisha Singh Verified
| Nature Verified
Abstract Pancreatic ductal adenocarcinoma (PDAC) has a poor survival rate and limited treatments. Agonistic CD40 antibodies are promising, but clinical trials have shown only modest efficacy and significant hepatotoxicity. We previously reported that IL-1 pathway blockade enhances CD40 agonist efficacy against melanoma by depleting polymorphonuclear myeloid-derived suppressor cells (PMN-MDSCs; CD11b+Ly6C+Ly6G+).
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Framework for cancer evolution profiling and interception in colorectal cancer: ASCEND-CRC program

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By Salvador Alonso, Kanwal Raghav, Van Morris, Kristin D. Alfaro-Munoz, Tanios S Bekaii-Saab, Timothy Cannon, Ryan B. Corcoran, Manju George, David Hsu, Christopher H. Lieu, Anirban Maitra, Dipen M. Maru, Jasmine A. McQuerry, David G. Menter, Jonathan Mizrahi, Kimmie Ng, Aparna R. Parikh, Kunal Rai, John Paul Shen, John Strickler, Alda Tam, Rona Yaeger, Ying Yuan, Xiling Shen, Andrea H. Bild, Scott Kopetz, Nicholas Duesbery, Michelle C. Sangar, Kenna R. Shaw, Ann D. Feehan, Guglielmo Vetere
| Cell Press Verified
Get full text access Log in, subscribe or purchase for full access. References 1. Sung, H. ∙ Ferlay, J. ∙ Siegel, R.L. ... Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries CA Cancer J. Clin. 2021; 71:209-249 2. Watanabe, J. ∙ Muro, K. ∙ Shitara, K. ...
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