Jia-Ying Wu

Ethyl acetate extract of the Musa nana flower inhibits osteoclastogenesis and suppresses NF-κB and MAPK pathways Minmin Tang, Yingjie Chen, Jia-Ying Wu, Aftab Amin, Xueming Zhou, Cai Jin, Guangying Chen and Zhiling Yu Abstract Banana flowers are consumed as a vegetable and traditionally used for managing several health problems including joint pain, a symptom of bone loss. Osteoclasts are key effector cells responsible for bone loss.

Abstract Fibroblast-like synoviocytes (FLS) play a pathogenic role in rheumatoid arthritis (RA). STAT3 signaling is activated in FLS of RA patients (RA-FLS), which in turn causes RA-FLS hyperproliferation. RL is a traditional remedy for treating inflammatory diseases in China. It comprises Rosae Multiflorae Fructus and Lonicerae Japonicae Flos. A standardized ethanolic extract of RL (RLE) has been shown to exert anti-arthritic effects in collagen-induced arthritis (CIA) rats.

PDF Int J Med Sci 2019; 16(5):729-740. doi:10.7150/ijms.32222 Research Paper Chia-Fang Tsai1,2, Jia-Ying Wu2, Yu-Wen Hsu 3 1. Department of Applied Cosmetology, National Tainan Junior College of Nursing, Tainan, Taiwan. 2. Department of Biotechnology, TransWorld University, Yunlin County, Taiwan. 3. Department of Optometry, Da-Yeh University, Changhua, Taiwan.