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Articles by Jiaming Li
Electronic Structure Engineering Enables Dynamic Interfacial Adaptation of Zinc Anodes
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adfm79395-sup-0001-SuppMat.docx27.9 MB Supporting File 1: adfm79395-sup-0001-SuppMat.docx. adfm79395-sup-0002-MovieS1.mp447.4 MB Supporting File 2: adfm79395-sup-0002-MovieS1.mp4.
Sensomics-Based Characterization of Flavor Maturation and Enhanced Ester Accumulation in Sufu Fermented With Leuconostoc lactis C2/15
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement Data will be made available on request. Supporting Information Filename Description jfds71513-sup-0001-TableS1-S5.docx80.5 KB Supporting File 1: jfds71513-sup-0001-TableS1-S5.docx References , , , , , and . 2021. “Sprouting Improves the Flavour Quality of Faba Bean Flours.” Food Chemistry 364: 130355. https://doi.org/10.1016/j.foodchem.2021.130355. , , , et al. 2023.
In Situ Protective Interface Construction via a Cyano-Ether Additive for Durable Zinc Metal Anodes
1 Introduction Aqueous zinc-ion batteries (AZIBs) offer promising prospects for large-scale energy storage due to their high theoretical capacity (820 mAh·g−1), intrinsic safety, cost-effectiveness, and abundant zinc resources [1-3]. However, their practical commercialization is hindered by the instability at the zinc anode/electrolyte interface.
Archipelago architecture and evolution of paclitaxel biosynthesis revealed by the Pseudotaxus chienii haplotype-resolved genome
Abstract Pseudotaxus chienii, the only species in the genus Pseudotaxus, is closely related to Taxus genus. Whether P. chienii can produce paclitaxel has long remained controversial. Here, we present a chromosome-level, haplotype-resolved genome of P. chienii, with each haplotype ( ~ 15.4 Gb) exhibiting high continuity and completeness.
De-localization of global cities: How advanced producer services exacerbate regional spatial inequality?
Advanced producer services (APS)—as key indicators of global city functions—reinforce the hub and control capacities of central cities within the global economy. However, their spatial benefits are unevenly distributed, often bypassing surrounding small- and medium-sized cities. This study investigates how the development of APS in 35 Chinese cities at or above the "sufficiency" level of global integration contributes to regional spatial inequality.
The Landscape of Long Non-Coding RNAs Provides Insights Into the Domestication and Improvement of Pear Fruit
1 Introduction In eukaryotes, approximately 75% of the genome can be transcribed, although merely 1%–2% of it can encode proteins [1-3]. This indicates that alongside a limited number of protein-coding genes (PCGs), there are still a large number of non-coding RNAs [4, 5].
Computer Science > Computation and Language
Financial sentiment analysis converts unstructured financial news into quantitative signals that can support market analysis and decision-making. Existing work on resource-efficient financial NLP has largely focused on compressing or adapting pretrained language models, with less attention to combining contextual representations with lightweight rule-derived features.
Optimal Retrofitting of Compressed Air Pipeline Networks via Edge-Addition Strategies Click to copy article link Article link copied!
Abstract Click to copy section linkSection link copied! Compressed air is an essential yet inefficient industrial energy source, accounting for approximately 10% of the total industrial energy consumption. Existing optimization measures predominantly focus on equipment operation and parameter tuning, failing to address the fundamental energy waste caused by structural ossification and inapplicability in aging compressed air systems (CASs).
Global, regional, and national burden of preterm birth 1990 to 2023, with projections of prevalence to 2050
Abstract Background: Preterm birth, the leading cause of under-five mortality, resulted in approximately 0.6 million neonatal deaths in 2023 and significant lifelong morbidity for survivors, including neurodevelopmental and respiratory impairments. This study aims to provide an updated assessment of age-standardized rates (ASR) in preterm birth prevalence, incidence, mortality, and disability-adjusted life-years (DALYs) from 1990 to 2023.
Author Correction: CHIT1-positive microglia drive motor neuron ageing in the primate spinal cord
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Correction to: Nature https://doi.org/10.1038/s41586-023-06783-1 Published online 31 October 2023 In the version of this article initially published, data from another experimental group were inadvertently entered into the corresponding Source Data table for Extended Data Fig. 9d. The Source Data and figure are now updated in the HTML and PDF versions of the article. The corrected data do not affect the results or conclusions of the paper. About this article Sun, S., Li, J., Wang, S. et al.
By Shuhui Sun, Jiaming Li, Si Ran Wang, Jingyi Li, Jie Ren, Zhaoshi Bao, Le Chang Sun, Xibo Ma, Fangshuo Zheng, Shuai Ma, Liang Sun, Min Wang, Yan Yu, Miyang Ma, Qiaoran Wang, Zhiyuan Chen, He Ma, Xuebao Wang, Zeming Wu, Kaowen Yan, Yuanhan Yang, Yixin Zhang, Sheng Zhang, Jinghui Lei, Zhao-Qian Teng, Chang-Mei Liu, Ge Bai, Yan-Jiang Wang, Jian Li, Xiaoqun Wang, Guoguang Zhao, Tao Jiang, Jing Qu, Weiqi Zhang, Guang-Hui Liu
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Nature
Verified
Bridged scaffold editing of carbocycles and heterocycles
Abstract Bridged frameworks are widely recognized as privileged motifs in natural products and pharmaceuticals, and their distinctive three-dimensional architectures often underpin target recognition and bioactivity. However, their preparation remains a formidable challenge, with most strategies relying on either linear multi-step syntheses or structurally specialized substrates.
Multimodal clocks of human aging
Impact of elevated pooling levels in basic medical insurance on insured individuals' inpatient service utilization—An equity analysis
Abstract Background: China has continuously promoted the transition of basic medical insurance from municipal-level pooling to provincial-level pooling to strengthen fund risk resilience, mutual-aid capacity, and benefit equalization.
Computer Science > Computer Vision and Pattern Recognition
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Human immune aging clock identifies RUNX1 as a decelerator of T cell senescence
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Keywords immunosenescence immune aging clock T cell senescence RUNX1 T cell receptor inflammaging rejuvenation Get full text access Log in, subscribe or purchase for full access. References 1. Iwasaki, A. ∙ Medzhitov, R. Control of adaptive immunity by the innate immune system Nat. Immunol. 2015; 16:343-353 2. Carroll, S.L. ∙ Pasare, C. ∙ Barton, G.M. Control of adaptive immunity by pattern recognition receptors Immunity. 2024; 57:632-648 3. Bolla, A.S. ∙ Priefer, R.
By Jiale Ping, Qin Qiao, Yun Li, Yanling Fan, Yutong Tian, Muzhao Xiong, Quan Zheng, Beier Jiang, Jiaming Li, Zheng Huang, Zikai Zheng, Xiaoyong Lu, Yiwen Hu, Yangqing Xu, Xiaoyan Sun, Qiaoran Wang, Si-jia Chen, Qi Wu, Lixiao Liu, Yuesheng Zuo, Shuhui Song, Si Qi Wang, Shuai Ma, Jing Qu, Yun-Gui Yang, Lan Jiang, Feng Zhang, Guang-Hui Liu, Weiqi Zhang, Dan-Dan Gao, Qinxin Tu, Liu-Jun Xu, Jin-Lin Ye, Cheng-Shui Chen
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Cell Press
Verified
Cartilage targeting hydrogel nanoplatform degrades BRD4 to alleviate osteoarthritis via Nav1.7 axis
Abstract Osteoarthritis (OA) is a common degenerative joint disease with limited disease-modifying therapies. Emerging evidence suggests that epigenetic dysregulation contributes to cartilage degeneration, but effective strategies to selectively target these pathways remain lacking. Here we show that the BRD4/Nav1.7 axis drives inflammatory and metabolic dysfunction in OA.
Generation of Femtosecond Optical Vortices Entanglement
Conflicts of Interest The authors declare no conflict of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. References 1, , and , “Structured Light,” Nature Photonics 15, no. 4 (2021): 253–262. 2, Structured Light and Its Applications: An Introduction to Phase-Structured Beams and Nanoscale Optical Forces (Academic press, 2011).
Janus Covalent Organic Framework Hydrogel Electrolyte via Multi‐Phase Regulation for Aqueous Zinc‐Ion Batteries
Conflicts of Interest The authors declare no conflicts of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adfm74141-sup-0001-SuppMat.docx10.7 MB Supporting File: adfm74141-sup-0001-SuppMat.docx. References 1, , , , , and , “Metal/Covalent Organic Frameworks for Aqueous Rechargeable Zinc-ion Batteries,” Science China Chemistry 67 (2024): 247.
Copper-Catalyzed Stereoselective Synthesis of Fluorinated 1,3-Dienes via Sequential Iodine-Fluorine Elimination | Organic Letters
Organic Letters Cite this: Org. Lett. 2025, XXXX, XXX Click to copy citationCitation copied! Learn about these metrics Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days. Citations are the number of other articles citing this article, calculated by Crossref and updated daily.
Copper-Catalyzed Stereoselective Synthesis of Fluorinated 1,3-Dienes via Sequential Iodine-Fluorine Elimination | Organic Letters
Cite Jump to ExpandCollapse LetterDecember 14, 2025 Copper-Catalyzed Stereoselective Synthesis of Fluorinated 1,3-Dienes via Sequential Iodine–Fluorine Elimination Click to copy article linkArticle link copied! Lili Zhao Lili Zhao School of Chemistry and Chemical Engineering, Nanchang University, Nanchang, Jiangxi 330031, China Chenyang Liu Chenyang Liu School of Chemistry and Chemical Engineering, Nanchang University, Nanchang, Jiangxi 330031, China Jinghong Zhang Jinghong Zhang School of...
Analytical Considerations for the Development of Plate-Based Proteomics Platforms Using Isobaric Labeling
Cite Jump to ExpandCollapse ArticleDecember 3, 2025 Analytical Considerations for the Development of Plate-Based Proteomics Platforms Using Isobaric Labeling Click to copy article linkArticle link copied! Jose Navarrete-Perea* Jose Navarrete-Perea Merck & Co., Inc., Cambridge, Massachusetts 02115, United States *Email: [email protected] Shideh Mirhadi Shideh Mirhadi Merck & Co., Inc., Cambridge, Massachusetts 02115, United States Jiaming Li Jiaming Li Merck & Co., Inc., Cambridge,...
Hydrogen‐Bond Donor Passivation Coupled with Inductive Electronic Modulation Enables Highly Reversible Zn Anodes via Interfacial Microenvironment Engineering
Conflict of Interest The authors declare no conflict of interest. Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request. Supporting Information Filename Description adfm72976-sup-0001-SuppMat.docx11.7 MB Supporting Information adfm72976-sup-0002-MovieS1.mp436 MB Supplemental Movie 1 References 1, , , Joule 2020, 4, 771. 2, , , , , , , , , , Energy Environ. Sci. 2021, 14, 3599. 3, , , , , , Mater.
Multi-omics analyses reveal regulatory networks underpinning metabolite biosynthesis in Nicotiana tabacum - Nature Communications
Abstract Tobacco is a significant industrial crop, serving as a model for plant science and a promising specie for the production of proteins and small molecules. However, system biology studies of tobacco under natural field cultivation conditions remain scarce. Here, we construct a genome-scale metabolic regulatory network through integration of dynamic transcriptomic and metabolomic profiles from field-grown tobacco leaves across two ecologically distinct regions.
An Unsung Hero - Li Jiaming (A Human Rights Defender)
LOS ANGELES, CALIFORNIA / ACCESS Newswire / September 9, 2025 / A Conscience of Tibet Li Jiaming, also known as Li Ang, is a respected human rights defender, a voice of conscience for Tibet, and a steadfast ally of democratic nations including India, New Zealand, the United States, Europe, South Korea, Japan, and Australia. He is a practitioner of the principles of Equality, Freedom, and the Rule of Law. Despite enduring immense suffering, Mr. Li has never wavered in his pursuit of justice.
Development and Mechanistic Exploration of Rhodium-Catalyzed Biaxially Atroposelective Click Chemistry
Abstract Click to copy section linkSection link copied! The construction of atropisomeric biaryls has emerged as a hot topic in organic chemistry, with remarkable advances being achieved. However, these studies mainly focus on the preparation of atropisomers with a single chiral axis, while the synthesis of atropisomers with more than one axis of chirality remains relatively rare, likely owing to the formidable challenges in establishing multiple axes with exquisite chiral control.
Comprehensive human proteome profiles across a 50-year lifespan reveal aging trajectories and signatures
1China National Center for Bioinformation and Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing 100101, China 2State Key Laboratory of Organ Regeneration and Reconstruction, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China 3Beijing Institute for Stem Cell and Regenerative Medicine, Beijing 100101, China 4Liver Transplant Center, Organ Transplant Center, West China Hospital of Sichuan University, Chengdu 610000, China 5Laboratory of Liver...
Preparation, Characterization, and Transformation Relationship of Gimeracil Crystal Forms P and L
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description crat70001-sup-0001-SuppMat.docx502.8 KB Supporting Information References 1, , , Cryst. Res. Technol. 2025, 60, 2400216. 2, , , Annu. Rev. Chem. Biomol. Eng. 2011, 2, 259. 3, , Chem. Soc. Rev. 2006, 35, 932. 4, Chem. Eng. Technol. 2006, 29, 233. 5, J. Pharm. Sci. 2011, 100, 1260. 6, , , J. Pharm. Biomed. Anal. 2011, 55, 618. 7, , Pharmaceutics 2020, 12, 34. 8, , Chem. Eng. Technol. 2017, 40, 1318. 9, , Adv. Drug Deliv.
Enhancing zinc anode stability via dual-additive electrolyte engineering
Enhancing zinc anode stability via dual-additive electrolyte engineering This study proposes a dual-additive electrolyte strategy based on NADH and KI to enhance the stability of the zinc anode. The specific adsorption of NADH on the zinc surface forms an effective anti-corrosion barrier, while I- homogenizes the Zn2+ flux, promoting stable deposition. The optimized electrolyte significantly improves the cycle life of zinc-ion hybrid capacitors, achieving stable operation for over 20000 cycles.
Covalent adduct Grob fragmentation underlies LSD1 demethylase-specific inhibitor mechanism of action and resistance - Nature Communications
Abstract Chromatin modifiers often work in concert with transcription factors (TFs) and other complex members, where they can serve both enzymatic and scaffolding functions. Due to this, active site inhibitors targeting chromatin modifiers may perturb both enzymatic and nonenzymatic functions.
Effects of Silver on the Strength in the T8 Condition and the Heat Resistance of Al–Cu–Li–Sc Alloy
Data Availability Statement The data that support the findings of this study are available from the corresponding author upon reasonable request.
Lentinan Reduces Transmission Efficiency of COVID-19 by Changing Aerodynamic Characteristic of Exhaled SARS-CoV-2 Aerosols in Golden Hamsters
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Printable graphene inks with polypropylene carbonate for low-surface-tension solvents and mild-temperature post-processing - Communications Materials
Abstract For dispersion stability, printable graphene inks commonly employ solvents with limited surface tensions or incorporate dispersant aids that require high-temperature post-processing, restricting printability and substrate compatibility. Here, printable graphene inks are introduced with low-surface-tension solvents and mild-temperature post-processing using polypropylene carbonate (PPC).
How can the “resource curse” be broken? Transition factor flows, the urban life cycle and value chain upgrades in resource-based cities - Humanities and Social Sciences Communications
Abstract Resource-based cities (RBCs) face persistent challenges from the “resource curse,” making industrial transition imperative for sustainable development. While the necessity of this transition is clear, the optimal pathways for implementation remain debated. This study investigates how external factor flows drive national value chain (NVC) upgrading in RBCs across different development stages.
TCN-GRU Based on Attention Mechanism for Solar Irradiance Prediction
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays
eLife Assessment The study provides a valuable showcase of a workflow to perform large-scale characterization of drug mechanisms of action using proteomics in which on-target and off-targets of 166 compounds using proteome solubility analysis in living cells and cell lysates were determined. The evidence supporting the claims of the authors is solid, however, the inclusion of more replicate experiments and more statistical rigor would have strengthened the study.
Origin, Evolution, and Diversification of the Expansin Family in Plants
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Horticulturae | Free Full-Text | Genome-Wide Identification of DREB Transcription Factor Family and Functional Analysis of PaDREB1D Associated with Low-Temperature Stress in Phalaenopsis aphrodite
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Informer-Based Model for Long-Term Ship Trajectory Prediction
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Exploring Firm Decision‐Making and Location Strategies in High‐Tech Manufacturing Relocation in Beijing: A Lifecycle Perspective
CONFLICT OF INTEREST STATEMENT No potential conflict of interest was reported by the authors. REFERENCES , & (2004), The Firm Relocation Decision: An Empirical Investigation. The Annals of Regional Science 38, pp. 335–347. , & (2019), Relocation of Economic Activity within Major Metropolitan Areas in Poland – Scale and Key Characteristics. In: A. Frenkel & E. Bendit, (eds.), Relocation of Economic Activity: Contemporary Theory and Practice in Local, Regional and Global Perspectives.
Achieving Dendrite‐Free and By‐Product‐Free Aqueous Zn‐Ion Battery Anode via Nicotinic Acid Electrolyte Additive with Molecule‐Ion Conversion Mechanism
Conflict of Interest The authors declare no conflict of interest. Supporting Information Filename Description smll202402595-sup-0001-SuppMat.docx3.5 MB Supporting Information References 1, , , , , , , , , , , , , Angew. Chem., Int. Ed. 2024, 136, 202318496. 2, , , , , , ACS Energy Lett. 2022, 7, 4168. 3, , , , , , , , , , Adv. Energy Mater. 2024, 2400367. 4, , , , ACS Energy Lett. 2020, 5, 3012. 5, , , , , , , , , , Adv. Energy Mater. 2023, 13, 2301743. 6, , , , , , , , Nanocarbon-Inorg.
Chemical and chemoenzymatic syntheses of sialyl Lewisa tetrasaccharide antigen
Chemical and chemoenzymatic syntheses of sialyl Lewisa tetrasaccharide antigen Sialyl Lewisa (sLea), also known as cancer antigen 19-9, is a tumor-associated carbohydrate antigen. In this article, chemical and chemoenzymatic syntheses of a tetrasaccharide glycan 1 structurally derived from sLea are reported.
Simultaneous Pore Detection and Morphological Features Extraction in Laser Powder Bed Fusion with Image Processing
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
DNA methylation clocks for estimating biological age in Chinese cohorts
Epigenetic clocks are accurate predictors of human chronological age based on the analysis of DNA methylation at specific CpG sites. However, available DNA methylation (DNAm) age predictors are based on datasets with limited ethnic representation. Moreover, a systematic comparison between DNAm data and other omics datasets has not yet been performed.
Metabolomic Profiling Reveals the Quality Variations in Citri Reticulatae Pericarpium (Citrus reticulata Blanco cv. Chachiensis) with Different Storage Ages in Response to “Candidatus Liberibacter Asiaticus” Infection
All articles published by MDPI are made immediately available worldwide under an open access license. No special permission is required to reuse all or part of the article published by MDPI, including figures and tables. For articles published under an open access Creative Common CC BY license, any part of the article may be reused without permission provided that the original article is clearly cited. For more information, please refer to https://www.mdpi.com/openaccess.
Multicomponent Reaction for Modular Assembly of Indole-Fused Heterocycles
Multicomponent Reaction for Modular Assembly of Indole-Fused Heterocycles Indoles are privileged chemical entities in natural products and drug discovery. Indole-fused heterocycles, particularly those seven-membered ones, have received emerging attention due to their distinctive chemical characteristics and wide spectrum of bioactivities. However, the synthetic access to these compounds is highly limited.
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