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Jiangying Yang

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Articles

Integrating bioinformatics analysis with molecular simulation to elucidate the therapeutic mechanism of Guizhi Fuling Wan for adenomyosis and endometriosis

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By Jingyi Wu, Xinting Li, Yanting Luo, Ying Gao, Yanfei Tao, Weiyong Hong, Shuikun Li, Jiangying Yang
| Nature Verified
Abstract To elucidate the mechanism of Guizhi Fuling Wan (GFW) against adenomyosis (AM) and endometriosis (EM) using an integrated approach combining network pharmacology, molecular docking, and molecular dynamics simulation. GFW components and their targets were retrieved from the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP) and SwissTargetPrediction databases, while AM and EM targets were obtained from GeneCards and Open Targets Platform.
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